Formation and repair of DNA lesions in kidneys of male mice after acute exposure to methyl chloride

The time-course of DNA lesions (DNA-protein cross-links, single-strand breaks) induced by high concentrations of methyl chloride (1000 ppm) was measured in renal tissue of male mice by means of the alkaline elution assay in order to gain an insight into repair processes. DNA-protein cross-links were...

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Veröffentlicht in:	Archives of toxicology 1990-01, Vol.64 (3), p.254-256
Hauptverfasser:	RISTAU, C, BOLT, H. M, VANGALA, R. R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Carcinogenesis, carcinogens and anticarcinogens Chemical agents DNA Damage DNA Repair DNA, Single-Stranded - drug effects DNA-Binding Proteins - metabolism Kidney - pathology Kidney Neoplasms - pathology Male Medical sciences Methyl Chloride - toxicity Mice Tumors
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