Novel Helicobacter pylori Sequencing Test Identifies High Rate of Clarithromycin Resistance

ABSTRACT Objectives: Eradication therapy selection for Helicobacter pylori gastritis requires knowledge of the local resistance rate to clarithromycin. There is minimal population‐based or regional data in the United States on pediatric clarithromycin resistance. Although commercial methods such as...

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Veröffentlicht in:	Journal of pediatric gastroenterology and nutrition 2014-07, Vol.59 (1), p.6-9
Hauptverfasser:	Mitui, Midori, Patel, Ashish, Leos, N. Kristine, Doern, Christopher D., Park, Jason Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Anti-Bacterial Agents - pharmacology antibiotic resistance Child Child, Preschool clarithromycin Clarithromycin - pharmacology DNA Mutational Analysis - methods DNA Primers DNA, Bacterial - analysis Drug Resistance, Bacterial - genetics Female formalin‐fixed paraffin‐embedded material Helicobacter Infections - drug therapy Helicobacter pylori Helicobacter pylori - drug effects Helicobacter pylori - genetics Humans Male Polymerase Chain Reaction Retreatment RNA, Ribosomal, 23S - genetics Sensitivity and Specificity Treatment Failure Young Adult
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