A man in his thirties with icterus and itching
We present a patient from South-East Asia who has been living in Norway for five years. He was referred to our department with jaundice caused by opisthorchiasis/clonorchiasis. This reason for jaundice is highly unusual in Europe. Worldwide, however about 35,000,000 people are infected. A male in hi...
Gespeichert in:
| Veröffentlicht in: | Tidsskrift for den Norske Lægeforening 2014-09, Vol.134 (17), p.1665-1668 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | nor |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1668 |
|---|---|
| container_issue | 17 |
| container_start_page | 1665 |
| container_title | Tidsskrift for den Norske Lægeforening |
| container_volume | 134 |
| creator | Huppertz-Hauss, Gert Brekke, Hanne Holmberg, Marte Skudal, Hilde |
| description | We present a patient from South-East Asia who has been living in Norway for five years. He was referred to our department with jaundice caused by opisthorchiasis/clonorchiasis. This reason for jaundice is highly unusual in Europe. Worldwide, however about 35,000,000 people are infected.
A male in his thirties, originally from South-East Asia, experienced diffuse itching for five weeks and painless jaundice for two weeks. Blood samples showed increasing cholestasis. Abdominal ultrasound, MRCP and computed tomography showed no sign of bile duct obstruction or liver tumour. Serological tests and liver biopsy revealed no infectious or autoimmune liver disease. ERCP showed normal bile ducts, but large quantities of typical hookworms in the duodenum. Stool samples showed at least one egg typical of Opisthorchis/Clonorchis and a large quantity of hookworm eggs. We interpreted these findings as parasite-induced obstruction of some of the small bile ducts. The patient recovered completely after treatment with Praziquantel.
Jaundice due to bile duct obstruction by opisthorchiasis/clonorchiasis is a well-known problem in South-East Asia. It may become more common in Europe as well as a result of increasing migration. Treatment with Praziquantel is simple and effective. |
| doi_str_mv | 10.4045/tidsskr.13.1215 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_1562662634</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1562662634</sourcerecordid><originalsourceid>FETCH-LOGICAL-p565-c9ee0401a6c8c437ac7c4b7c97b6689aafe511f70d09e448aaffed840a07507e3</originalsourceid><addsrcrecordid>eNo1j01LxDAURYMgzji6didZuml9aT67HAYdhQE3sy9p-mqjbacmKeK_t-AIFw5cDhcuIXcMcgFCPibfxPgZcsZzVjB5QdZgQGcaSrUi1zF-ABRGsfKKrApZFFxpuSb5lg52pH6knY80dT4kj5F--9RR7xKGOVI7NtQn1_nx_YZctraPeHvmhhyfn467l-zwtn_dbQ_ZJJXMXIkIAphVzjjBtXXaiVq7UtdKmdLaFiVjrYYGShTCLEWLjRFgQUvQyDfk4W92CqevGWOqBh8d9r0d8TTHiklVqCVcLOr9WZ3rAZtqCn6w4af6v8h_AaO2UQU</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1562662634</pqid></control><display><type>article</type><title>A man in his thirties with icterus and itching</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Norart Open Access</source><creator>Huppertz-Hauss, Gert ; Brekke, Hanne ; Holmberg, Marte ; Skudal, Hilde</creator><creatorcontrib>Huppertz-Hauss, Gert ; Brekke, Hanne ; Holmberg, Marte ; Skudal, Hilde</creatorcontrib><description>We present a patient from South-East Asia who has been living in Norway for five years. He was referred to our department with jaundice caused by opisthorchiasis/clonorchiasis. This reason for jaundice is highly unusual in Europe. Worldwide, however about 35,000,000 people are infected.
A male in his thirties, originally from South-East Asia, experienced diffuse itching for five weeks and painless jaundice for two weeks. Blood samples showed increasing cholestasis. Abdominal ultrasound, MRCP and computed tomography showed no sign of bile duct obstruction or liver tumour. Serological tests and liver biopsy revealed no infectious or autoimmune liver disease. ERCP showed normal bile ducts, but large quantities of typical hookworms in the duodenum. Stool samples showed at least one egg typical of Opisthorchis/Clonorchis and a large quantity of hookworm eggs. We interpreted these findings as parasite-induced obstruction of some of the small bile ducts. The patient recovered completely after treatment with Praziquantel.
Jaundice due to bile duct obstruction by opisthorchiasis/clonorchiasis is a well-known problem in South-East Asia. It may become more common in Europe as well as a result of increasing migration. Treatment with Praziquantel is simple and effective.</description><identifier>EISSN: 0807-7096</identifier><identifier>DOI: 10.4045/tidsskr.13.1215</identifier><identifier>PMID: 25223675</identifier><language>nor</language><publisher>Norway</publisher><subject>Adult ; Ancylostoma - isolation & purification ; Animals ; Anthelmintics - therapeutic use ; Asia, Southeastern - ethnology ; Bile Ducts - parasitology ; Clonorchiasis - diagnosis ; Clonorchiasis - drug therapy ; Clonorchis sinensis - growth & development ; Clonorchis sinensis - isolation & purification ; Duodenum - parasitology ; Humans ; Jaundice - parasitology ; Male ; Norway ; Opisthorchiasis - diagnosis ; Opisthorchiasis - drug therapy ; Opisthorchis - growth & development ; Opisthorchis - isolation & purification ; Praziquantel - therapeutic use ; Pruritus - parasitology</subject><ispartof>Tidsskrift for den Norske Lægeforening, 2014-09, Vol.134 (17), p.1665-1668</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,860,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25223675$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Huppertz-Hauss, Gert</creatorcontrib><creatorcontrib>Brekke, Hanne</creatorcontrib><creatorcontrib>Holmberg, Marte</creatorcontrib><creatorcontrib>Skudal, Hilde</creatorcontrib><title>A man in his thirties with icterus and itching</title><title>Tidsskrift for den Norske Lægeforening</title><addtitle>Tidsskr Nor Laegeforen</addtitle><description>We present a patient from South-East Asia who has been living in Norway for five years. He was referred to our department with jaundice caused by opisthorchiasis/clonorchiasis. This reason for jaundice is highly unusual in Europe. Worldwide, however about 35,000,000 people are infected.
A male in his thirties, originally from South-East Asia, experienced diffuse itching for five weeks and painless jaundice for two weeks. Blood samples showed increasing cholestasis. Abdominal ultrasound, MRCP and computed tomography showed no sign of bile duct obstruction or liver tumour. Serological tests and liver biopsy revealed no infectious or autoimmune liver disease. ERCP showed normal bile ducts, but large quantities of typical hookworms in the duodenum. Stool samples showed at least one egg typical of Opisthorchis/Clonorchis and a large quantity of hookworm eggs. We interpreted these findings as parasite-induced obstruction of some of the small bile ducts. The patient recovered completely after treatment with Praziquantel.
Jaundice due to bile duct obstruction by opisthorchiasis/clonorchiasis is a well-known problem in South-East Asia. It may become more common in Europe as well as a result of increasing migration. Treatment with Praziquantel is simple and effective.</description><subject>Adult</subject><subject>Ancylostoma - isolation & purification</subject><subject>Animals</subject><subject>Anthelmintics - therapeutic use</subject><subject>Asia, Southeastern - ethnology</subject><subject>Bile Ducts - parasitology</subject><subject>Clonorchiasis - diagnosis</subject><subject>Clonorchiasis - drug therapy</subject><subject>Clonorchis sinensis - growth & development</subject><subject>Clonorchis sinensis - isolation & purification</subject><subject>Duodenum - parasitology</subject><subject>Humans</subject><subject>Jaundice - parasitology</subject><subject>Male</subject><subject>Norway</subject><subject>Opisthorchiasis - diagnosis</subject><subject>Opisthorchiasis - drug therapy</subject><subject>Opisthorchis - growth & development</subject><subject>Opisthorchis - isolation & purification</subject><subject>Praziquantel - therapeutic use</subject><subject>Pruritus - parasitology</subject><issn>0807-7096</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1j01LxDAURYMgzji6didZuml9aT67HAYdhQE3sy9p-mqjbacmKeK_t-AIFw5cDhcuIXcMcgFCPibfxPgZcsZzVjB5QdZgQGcaSrUi1zF-ABRGsfKKrApZFFxpuSb5lg52pH6knY80dT4kj5F--9RR7xKGOVI7NtQn1_nx_YZctraPeHvmhhyfn467l-zwtn_dbQ_ZJJXMXIkIAphVzjjBtXXaiVq7UtdKmdLaFiVjrYYGShTCLEWLjRFgQUvQyDfk4W92CqevGWOqBh8d9r0d8TTHiklVqCVcLOr9WZ3rAZtqCn6w4af6v8h_AaO2UQU</recordid><startdate>20140916</startdate><enddate>20140916</enddate><creator>Huppertz-Hauss, Gert</creator><creator>Brekke, Hanne</creator><creator>Holmberg, Marte</creator><creator>Skudal, Hilde</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20140916</creationdate><title>A man in his thirties with icterus and itching</title><author>Huppertz-Hauss, Gert ; Brekke, Hanne ; Holmberg, Marte ; Skudal, Hilde</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p565-c9ee0401a6c8c437ac7c4b7c97b6689aafe511f70d09e448aaffed840a07507e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>nor</language><creationdate>2014</creationdate><topic>Adult</topic><topic>Ancylostoma - isolation & purification</topic><topic>Animals</topic><topic>Anthelmintics - therapeutic use</topic><topic>Asia, Southeastern - ethnology</topic><topic>Bile Ducts - parasitology</topic><topic>Clonorchiasis - diagnosis</topic><topic>Clonorchiasis - drug therapy</topic><topic>Clonorchis sinensis - growth & development</topic><topic>Clonorchis sinensis - isolation & purification</topic><topic>Duodenum - parasitology</topic><topic>Humans</topic><topic>Jaundice - parasitology</topic><topic>Male</topic><topic>Norway</topic><topic>Opisthorchiasis - diagnosis</topic><topic>Opisthorchiasis - drug therapy</topic><topic>Opisthorchis - growth & development</topic><topic>Opisthorchis - isolation & purification</topic><topic>Praziquantel - therapeutic use</topic><topic>Pruritus - parasitology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Huppertz-Hauss, Gert</creatorcontrib><creatorcontrib>Brekke, Hanne</creatorcontrib><creatorcontrib>Holmberg, Marte</creatorcontrib><creatorcontrib>Skudal, Hilde</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Tidsskrift for den Norske Lægeforening</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Huppertz-Hauss, Gert</au><au>Brekke, Hanne</au><au>Holmberg, Marte</au><au>Skudal, Hilde</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A man in his thirties with icterus and itching</atitle><jtitle>Tidsskrift for den Norske Lægeforening</jtitle><addtitle>Tidsskr Nor Laegeforen</addtitle><date>2014-09-16</date><risdate>2014</risdate><volume>134</volume><issue>17</issue><spage>1665</spage><epage>1668</epage><pages>1665-1668</pages><eissn>0807-7096</eissn><abstract>We present a patient from South-East Asia who has been living in Norway for five years. He was referred to our department with jaundice caused by opisthorchiasis/clonorchiasis. This reason for jaundice is highly unusual in Europe. Worldwide, however about 35,000,000 people are infected.
A male in his thirties, originally from South-East Asia, experienced diffuse itching for five weeks and painless jaundice for two weeks. Blood samples showed increasing cholestasis. Abdominal ultrasound, MRCP and computed tomography showed no sign of bile duct obstruction or liver tumour. Serological tests and liver biopsy revealed no infectious or autoimmune liver disease. ERCP showed normal bile ducts, but large quantities of typical hookworms in the duodenum. Stool samples showed at least one egg typical of Opisthorchis/Clonorchis and a large quantity of hookworm eggs. We interpreted these findings as parasite-induced obstruction of some of the small bile ducts. The patient recovered completely after treatment with Praziquantel.
Jaundice due to bile duct obstruction by opisthorchiasis/clonorchiasis is a well-known problem in South-East Asia. It may become more common in Europe as well as a result of increasing migration. Treatment with Praziquantel is simple and effective.</abstract><cop>Norway</cop><pmid>25223675</pmid><doi>10.4045/tidsskr.13.1215</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | EISSN: 0807-7096 |
| ispartof | Tidsskrift for den Norske Lægeforening, 2014-09, Vol.134 (17), p.1665-1668 |
| issn | 0807-7096 |
| language | nor |
| recordid | cdi_proquest_miscellaneous_1562662634 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Norart Open Access |
| subjects | Adult Ancylostoma - isolation & purification Animals Anthelmintics - therapeutic use Asia, Southeastern - ethnology Bile Ducts - parasitology Clonorchiasis - diagnosis Clonorchiasis - drug therapy Clonorchis sinensis - growth & development Clonorchis sinensis - isolation & purification Duodenum - parasitology Humans Jaundice - parasitology Male Norway Opisthorchiasis - diagnosis Opisthorchiasis - drug therapy Opisthorchis - growth & development Opisthorchis - isolation & purification Praziquantel - therapeutic use Pruritus - parasitology |
| title | A man in his thirties with icterus and itching |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-20T20%3A14%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20man%20in%20his%20thirties%20with%20icterus%20and%20itching&rft.jtitle=Tidsskrift%20for%20den%20Norske%20L%C3%A6geforening&rft.au=Huppertz-Hauss,%20Gert&rft.date=2014-09-16&rft.volume=134&rft.issue=17&rft.spage=1665&rft.epage=1668&rft.pages=1665-1668&rft.eissn=0807-7096&rft_id=info:doi/10.4045/tidsskr.13.1215&rft_dat=%3Cproquest_pubme%3E1562662634%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1562662634&rft_id=info:pmid/25223675&rfr_iscdi=true |