Freshly fractured quartz inhalation leads to enhanced lung injury and inflammation. Potential role of free radicals

Silicosis is a devastating pulmonary disease that continues to occur in industrial workplaces. Its pathogenesis is under critical evaluation, and this report provides new concepts on the possible early events that occur in lungs resulting from the inhalation of freshly fractured versus aged quartz i...

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Veröffentlicht in:	American journal of respiratory and critical care medicine 1995-09, Vol.152 (3), p.1003-1009
Hauptverfasser:	Vallyathan, V, Castranova, V, Pack, D, Leonard, S, Shumaker, J, Hubbs, A F, Shoemaker, D A, Ramsey, D M, Pretty, J R, McLaurin, J L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bronchoalveolar Lavage Fluid - chemistry Dust - adverse effects Inflammation - pathology Inflammation - physiopathology Lipid Peroxidation Lung - pathology Male Quartz - adverse effects Rats Rats, Inbred F344 Reactive Oxygen Species - adverse effects Time Factors
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