An isogenic haemolysin‐deficient mutant of Haemophilus ducreyi lacks the ability to produce cytopathic effects on human foreskin fibroblasts

The haemolysin of Haemophilus ducreyi is the newest member of the Proteus/Serratia family of pore‐forming toxins. In order to assess the role of the haemolysin in virulence, we constructed an isogenic haemolysin‐deficient mutant of H. ducreyi strain 35000. This strain, designated 35000‐3, lacks dete...

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Veröffentlicht in:	Molecular microbiology 1996-07, Vol.21 (1), p.13-19
Hauptverfasser:	Palmer, Katherine L., Goldman, William E., Munson, Jr, Robert S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line Chancroid - etiology Fibroblasts Haemophilus ducreyi Haemophilus ducreyi - genetics Haemophilus ducreyi - pathogenicity HeLa Cells Hemolysin Proteins - genetics Hemolysin Proteins - toxicity Humans Male Mutation Plasmids - genetics Virulence - genetics
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