17p (p53) allelic losses, 4N (G sub(2)/tetraploid) populations, and progression to aneuploidy in Barrett's esophagus

Increased 4N (G sub(2)/tetraploid) cell populations have been postulated to be genetically unstable intermediates in the progression to many cancers, but the mechanism by which they develop and their relationship to instability have been difficult to investigate in humans in vivo. Barrett's eso...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1996-07, Vol.93 (14), p.7081-7084
Hauptverfasser:	Galipeau, P C, Cowan, D S, Sanchez, CA, Barrett, M T, Emond, MJ, Levine, D S, Rabinovitch, P S, Reid, B J
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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