Thalidomide derivatives and the immune system 6. Effects of two derivatives with no obvious teratogenic potency on the pattern of integrins and other surface receptors on blood cells of marmosets

The two thalidomide (Thd) derivatives B-EM12 and phthalimidophthalimide (Phtpht), which exhibit no obvious teratogenicity, were tested for their ability to induce changes in the pattern of lymphocyte subpopulations and especially changes in integrin receptors, in marmosets ( Callithrix jacchus). Pre...

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Veröffentlicht in:	Life sciences (1973) 1996, Vol.58 (4), p.337-348
Hauptverfasser:	Nogueira, Ana Cristina, Neubert, Reinhard, Felies, Annegret, Jacob-Muller, Ursula, Frankus, Ernst, Neubert, Diether
Format:	Artikel
Sprache:	eng
Schlagworte:	2-phthalimidophthalimide adhesion receptors Animals Antigens, CD - metabolism B-EM12 Callithrix Callithrix jacchus Cell Adhesion Molecules - metabolism Flow Cytometry Immune System Integrins - metabolism Leukocytes, Mononuclear - drug effects Leukocytes, Mononuclear - metabolism Lymphocyte Subsets - drug effects marmoset Membrane Glycoproteins Membrane Proteins - metabolism Platelet Glycoprotein GPIb-IX Complex Receptors, Cell Surface - metabolism Teratogens - toxicity thalidomide Thalidomide - analogs & derivatives Thalidomide - toxicity
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