A monotonic and prognostic genomic signature from fibroblasts for colorectal cancer initiation, progression, and metastasis

The differential gene expression patterns between normal colonic fibroblasts (NCF), carcinoma-associated fibroblasts from primary tumors (CAF-PT), and CAFs from hepatic metastasis (CAF-LM) are hypothesized to be useful for predicting relapse in primary tumors. A transcriptomic profile of NCF (n = 9)...

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Veröffentlicht in:	Molecular cancer research 2014-09, Vol.12 (9), p.1254-1266
Hauptverfasser:	Berdiel-Acer, Mireia, Cuadras, Daniel, Díaz-Maroto, Natalia Guillén, Sanjuan, Xavier, Serrano, Teresa, Berenguer, Antoni, Moreno, Victor, Gonçalves-Ribeiro, Samuel, Salazar, Ramon, Villanueva, Alberto, Molleví, David G
Format:	Artikel
Sprache:	eng
Schlagworte:	Carcinogenesis - genetics Colorectal Neoplasms - diagnosis Colorectal Neoplasms - genetics Colorectal Neoplasms - pathology Fibroblasts - metabolism Fibroblasts - pathology Gene Expression Regulation, Neoplastic Genome, Human Humans Neoplasm Metastasis Neoplasm Recurrence, Local - genetics Neoplasm Recurrence, Local - pathology Prognosis Transcriptome
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