Stage-dependent nigral neuronal loss in incidental Lewy body and Parkinson's disease

To gain a better understanding of the significance of α‐synuclein pathological conditions during disease progression in Parkinson's disease, we investigated whether 1) nigral neuronal loss in incidental Lewy body disease and Parkinson's disease donors is associated with the local burden α‐...

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Veröffentlicht in:	Movement disorders 2014-09, Vol.29 (10), p.1244-1251
Hauptverfasser:	Dijkstra, Anke A., Voorn, Pieter, Berendse, Henk W., Groenewegen, Henk J., Rozemuller, Annemieke J.M., van de Berg, Wilma D.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over alpha-Synuclein - metabolism Analysis of Variance Braak α-synuclein staging Case-Control Studies Cell Count Cell Death Disease Progression Female Humans Lewy Body Disease - pathology Male Medical research Movement disorders Netherlands Neurons - metabolism Neurons - pathology Parkinson Disease - pathology Parkinson's disease Severity of Illness Index Statistics as Topic substantia nigra Substantia Nigra - pathology α-synuclein
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