Comparative cost-effectiveness of bevacizumab-irinotecan-fluorouracil versus irinotecan-fluorouracil in first-line metastatic colorectal cancer

Purpose To evaluate the cost-effectiveness of the addition of bevacizumab to the irinotecan-fluorouracil (Douillard regimen-CPT-FUFA-) in first-line treatment of metastatic colorectal cancer in a single-institution population. Methods Controlled, nonrandomized retrospective observational study. Trea...

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Veröffentlicht in:	Journal of oncology pharmacy practice 2014-10, Vol.20 (5), p.341-350
Hauptverfasser:	Ruiz-Millo, Oreto, Albert-Mari, Asuncion, Sendra-Garcia, Ana, Jimenez-Torres, N Victor
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antibodies, Monoclonal, Humanized - administration & dosage Antibodies, Monoclonal, Humanized - economics Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - economics Antineoplastic Combined Chemotherapy Protocols - therapeutic use Bevacizumab Camptothecin - administration & dosage Camptothecin - analogs & derivatives Camptothecin - economics Chemotherapy Chi-Square Distribution Colorectal cancer Colorectal Neoplasms - drug therapy Colorectal Neoplasms - economics Colorectal Neoplasms - mortality Colorectal Neoplasms - pathology Cost analysis Cost-Benefit Analysis Disease Progression Disease-Free Survival Drug Costs Female Fluorouracil - administration & dosage Fluorouracil - economics Humans Kaplan-Meier Estimate Male Metastasis Middle Aged Pharmacology Proportional Hazards Models Retrospective Studies Risk Factors Spain Time Factors Treatment Outcome
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