BCOR-CCNB3 (Ewing-like) Sarcoma: A Clinicopathologic Analysis of 10 Cases, In Comparison With Conventional Ewing Sarcoma

BCOR-CCNB3 fusion transcripts resulting from an X-chromosomal paracentric inversion were recently identified in a series of unclassifiable soft tissue and bone sarcomas with Ewing sarcoma–like morphology. The morphologic and clinical features of these sarcomas are, as yet, not well characterized. He...

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Veröffentlicht in:	The American journal of surgical pathology 2014-10, Vol.38 (10), p.1307-1318
Hauptverfasser:	Puls, Florian, Niblett, Angela, Marland, Gillian, Gaston, Czar Louie L, Douis, Hassan, Mangham, D Chas, Sumathi, Vaiyapuri P, Kindblom, Lars-Gunnar
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Biomarkers, Tumor - analysis Biomarkers, Tumor - genetics Biopsy Bone Neoplasms - chemistry Bone Neoplasms - diagnosis Bone Neoplasms - genetics Bone Neoplasms - mortality Bone Neoplasms - pathology Child Cyclin B - analysis Cyclin B - genetics Gene Fusion Humans Immunohistochemistry Kaplan-Meier Estimate Magnetic Resonance Imaging Male Predictive Value of Tests Prognosis Proportional Hazards Models Proto-Oncogene Proteins - analysis Proto-Oncogene Proteins - genetics Repressor Proteins - analysis Repressor Proteins - genetics Reverse Transcriptase Polymerase Chain Reaction Sarcoma, Ewing - chemistry Sarcoma, Ewing - diagnosis Sarcoma, Ewing - genetics Sarcoma, Ewing - mortality Sarcoma, Ewing - secondary Time Factors Translocation, Genetic
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