Gene Transfer into the Mouse Retina Mediated by an Adeno-Associated Viral Vector

Gene transfer to photoreceptor cells may provide a means for arresting the retinal degeneration that is characteristic of many inherited causes of blindness, including retinitis pigmentosa (RP). However, transduction of photoreceptors has to date been inefficient, and further limited by toxicity and...

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Veröffentlicht in:Human molecular genetics 1996-05, Vol.5 (5), p.591-594
Hauptverfasser: Ali, Robin R., Reichel, Martin B., Thrasher, Adrian J., Levinsky, Roland J., Kinnon, Christine, Kanuga, Naheed, Hunt, David M., Bhattacharya, Shomi S.
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Sprache:eng
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