Malignant peripheral nerve sheath tumour of the infra-orbital nerve

Malignant peripheral nerve sheath tumour of the infra-orbital nerve

A malignant peripheral nerve sheath tumour (MPNST) is an uncommon neoplasm that rarely involves the head and neck region. It is even more infrequent for these tumours to affect cranial nerves. We report the case of a 53-year-old man who presented a MPNST involving the infra-orbital nerve, which exte...

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Veröffentlicht in:Neurocirugía (Asturias, Spain) Spain), 2014-09, Vol.25 (5), p.240-243
Hauptverfasser: González-Orús Álvarez-Morujo, Ricardo, García Leal, Roberto, Lasso Vázquez, José María, Scola Yurrita, Barolomé
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container_issue 5
container_start_page 240
container_title Neurocirugía (Asturias, Spain)
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creator González-Orús Álvarez-Morujo, Ricardo
García Leal, Roberto
Lasso Vázquez, José María
Scola Yurrita, Barolomé
description A malignant peripheral nerve sheath tumour (MPNST) is an uncommon neoplasm that rarely involves the head and neck region. It is even more infrequent for these tumours to affect cranial nerves. We report the case of a 53-year-old man who presented a MPNST involving the infra-orbital nerve, which extended through the orbit and the base of the skull, progressing intracranially. Histological studies identified the tumour as an MPNST. Response to radiotherapy was not complete and radical surgical resection was impossible, so the patient died 10months later. This rare case of MPNST with intracranial involvement illustrates the dismal prognosis for patients with these lesions. Prognosis is poor because of the difficulty of performing radical surgery with free margins in these locations.
doi_str_mv 10.1016/j.neucir.2014.02.002
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title Malignant peripheral nerve sheath tumour of the infra-orbital nerve
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