p53 and ribosome biogenesis stress: The essentials

Cell proliferation and cell growth are two tightly linked processes, as the proliferation program cannot be executed without proper accumulation of cell mass, otherwise endangering the fate of the two daughter cells. It is therefore not surprising that ribosome biogenesis, a key element in cell grow...

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Veröffentlicht in:	FEBS letters 2014-08, Vol.588 (16), p.2571-2579
Hauptverfasser:	Golomb, Lior, Volarevic, Sinisa, Oren, Moshe
Format:	Artikel
Sprache:	eng
Schlagworte:	5′ terminal oligopyrimidine 5′TOP ActD Actinomycin D Animals Cell Nucleolus - metabolism DBA Diamond Blackfan anemia Humans MDS Molecular Targeted Therapy myelodysplastic syndrome Neoplasms - drug therapy Neoplasms - metabolism Neoplasms - pathology NOR nucleolar organizing regions Nucleolus p53 post translational modifications PTM Ribosomal protein ribosomal proteins Ribosome biogenesis Ribosomes - metabolism RPs Schwachman–Diamond syndrome SDS Tumor Suppressor Protein p53 - metabolism
Online-Zugang:	Volltext
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