Insulin Administration May Trigger Type 1 Diabetes in Japanese Type 2 Diabetes Patients With Type 1 Diabetes High-Risk HLA Class II and the Insulin Gene VNTR Genotype

Context: Insulin administration causes various types of immune responses to insulin. We previously reported three cases of type 1 diabetes mellitus (T1DM) triggered by insulin administration in Japanese type 2 diabetes mellitus patients. Objective: The objective of this study was to collect informat...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2014-09, Vol.99 (9), p.E1793-E1797
Hauptverfasser:	Nishida, Wataru, Nagata, Masao, Imagawa, Akihisa, Hanafusa, Toshiaki, Ohashi, Jun, Takahashi, Kenji, Suehiro, Tadashi, Yamada, Yuya, Chujo, Daisuke, Kawasaki, Eiji, Kawamura, Ryoichi, Onuma, Hiroshi, Osawa, Haruhiko, Makino, Hideichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antibodies - immunology Asian Continental Ancestry Group - ethnology Asian Continental Ancestry Group - genetics Diabetes Mellitus, Type 1 - chemically induced Diabetes Mellitus, Type 1 - ethnology Diabetes Mellitus, Type 1 - genetics Diabetes Mellitus, Type 2 - drug therapy Diabetes Mellitus, Type 2 - ethnology Diabetes Mellitus, Type 2 - genetics Female Genetic Predisposition to Disease - ethnology Genetic Predisposition to Disease - genetics Genotype Histocompatibility Antigens Class II - genetics Histocompatibility Antigens Class II - immunology Humans Hypoglycemic Agents - adverse effects Hypoglycemic Agents - immunology Insulin - adverse effects Insulin - genetics Insulin - immunology Male Middle Aged Minisatellite Repeats - genetics Risk Factors
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