Increased Th17 cells and IL-17 in rats with traumatic optic neuropathy

T helper 17 (Th17) cells are strong inducers of numerous autoimmune diseases and inflammation. However, the role of Th17 cells and interleukin (IL)-17 in traumatic optic neuropathy (TON) are yet to be elucidated. In the present study, a rat model of TON was established using a fluid percussion brain...

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Veröffentlicht in:	Molecular medicine reports 2014-10, Vol.10 (4), p.1954-1958
Hauptverfasser:	ZHENG, HUABIN, ZHANG, ZHUHONG, LUO, NA, LIU, YUANYUAN, CHEN, QINGZHONG, YAN, HUA
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autoimmune diseases Brain injury Cytokines Disease Models, Animal Head injuries Helper cells Immunoglobulins Immunohistochemistry Inflammation Interleukin 17 Interleukin-17 - metabolism Interleukins Lymphocytes Lymphocytes T Manufacturers Medical prognosis Optic nerve Optic Nerve Injuries - metabolism Optic Nerve Injuries - physiopathology Optic neuropathy Pathogenesis Physiological aspects Proteins Rats Rats, Sprague-Dawley Retina Retina - metabolism Rodents Spleen Standard deviation T cells T helper 17 cells Th17 Cells - cytology Th17 Cells - immunology Trauma traumatic optic neuropathy
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