Hepatitis B virus x protein induces autophagy via activating death-associated protein kinase

Summary Hepatitis B virus x protein (HBX), a product of hepatitis B virus (HBV), is a multifunctional protein that regulates viral replication and various cellular functions. Recently, HBX has been shown to induce autophagy; however, the responsible mechanism is not fully known. In this study, we es...

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Veröffentlicht in:	Journal of viral hepatitis 2014-09, Vol.21 (9), p.642-649
Hauptverfasser:	Zhang, H.-T, Chen, G. G., Hu, B.-G., Zhang, Z.-Y., Yun, J.-P, He, M.-L., Lai, P. B. S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Regulatory Proteins - metabolism Autophagy Beclin-1 Beclin1 Cell Line death-associated protein kinase Death-Associated Protein Kinases - metabolism Hepatitis Hepatitis B virus Hepatitis B virus - physiology hepatitis B virus x protein Host-Pathogen Interactions Humans Kinases Membrane Proteins - metabolism Proteins Trans-Activators - metabolism
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