Flux response of glycolysis and storage metabolism during rapid feast/famine conditions in Penicillium chrysogenum using dynamic super(13)C labeling

The scale-up of fermentation processes frequently leads to a reduced productivity compared to small-scale screening experiments. Large-scale mixing limitations that lead to gradients in substrate and oxygen availability could influence the microorganism performance. Here, the impact of substrate gra...

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Veröffentlicht in:	Biotechnology journal 2014-03, Vol.9 (3), p.372-385
Hauptverfasser:	de Jonge, Lodewijk, Buijs, Nicolaas AA, Heijnen, Joseph J, van Gulik, Walter M, Abate, Alessandro, Wahl, SAljoscha
Format:	Artikel
Sprache:	eng
Schlagworte:	Penicillium chrysogenum
Online-Zugang:	Volltext
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