Bipolar depressed patients show both failure to activate and failure to de-activate during performance of a working memory task

Abstract Background Bipolar depression has been found to be associated with changes in prefrontal cortex activity during performance of cognitive tasks. However, the role of task-related de-activations has been little investigated. Method Forty-one bipolar depressed patients and 41 matched normal co...

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Veröffentlicht in:	Journal of affective disorders 2013-06, Vol.148 (2), p.170-178
Hauptverfasser:	Fernández-Corcuera, Paloma, Salvador, Raymond, Monté, Gemma C, Salvador Sarró, S, Goikolea, José M, Amann, Benedikt, Moro, Noemí, Sans-Sansa, Bibiana, Ortiz-Gil, Jordi, Vieta, Eduard, Maristany, Teresa, McKenna, Peter J, Pomarol-Clotet, Edith
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adult and adolescent clinical studies Biological and medical sciences Bipolar affective disorder Bipolar depression Bipolar Disorder - physiopathology Bipolar disorders Case-Control Studies Cerebellum - physiopathology Cortex Default mode network Depression Dysfunction Female Functional MRI Humans Magnetic Resonance Imaging Male Medical sciences Memory, Short-Term - physiology Middle Aged Mood disorders Prefrontal Cortex - physiopathology Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Task performance Task Performance and Analysis Working memory
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