Noninvasive prenatal diagnosis experience in the Çukurova Region of Southern Turkey: detecting paternal mutations of sickle cell anemia and [beta]-thalassemia in cell-free fetal DNA using high-resolution melting analysis

Objective This study used a high-resolution melting (HRM) technique to detect paternal mutations for the noninvasive prenatal diagnosis (NIPD) of [beta]-thalassemia and sickle cell anemia (HbS). We also determined the levels of cell-free fetal DNA and total cell-free DNA. Methods We used the HRM tec...

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Veröffentlicht in:	Prenatal diagnosis 2013-11, Vol.33 (11), p.1054-1062
Hauptverfasser:	Yenilmez, Ebru Dundar, Tuli, Abdullah, Evruke, I Cuneyt
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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