Semantic processing and response inhibition
The present study examined functional MRI (fMRI) BOLD signal changes in response to object categorization during response selection and inhibition. Young adults (N=16) completed a Go/NoGo task with varying object categorization requirements while fMRI data were recorded. Response inhibition elicited...
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| Veröffentlicht in: | Neuroreport 2013-11, Vol.24 (16), p.889-893 |
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| container_title | Neuroreport |
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| creator | Chiang, Hsueh-Sheng Motes, Michael A. Mudar, Raksha A. Rao, Neena K. Mansinghani, Sethesh Brier, Matthew R. Maguire, Mandy J. Kraut, Michael A. Hart, John |
| description | The present study examined functional MRI (fMRI) BOLD signal changes in response to object categorization during response selection and inhibition. Young adults (N=16) completed a Go/NoGo task with varying object categorization requirements while fMRI data were recorded. Response inhibition elicited increased signal change in various brain regions, including medial frontal areas, compared with response selection. BOLD signal in an area within the right angular gyrus was increased when higher-order categorization was mandated. In addition, signal change during response inhibition varied with categorization requirements in the left inferior temporal gyrus (lIT). lIT-mediated response inhibition when inhibiting the response only required lower-order categorization, but lIT mediated both response selection and inhibition when selecting and inhibiting the response required higher-order categorization. The findings characterized mechanisms mediating response inhibition associated with semantic object categorization in the ‘what’ visual object memory system. |
| doi_str_mv | 10.1097/WNR.0000000000000014 |
| format | Article |
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Young adults (N=16) completed a Go/NoGo task with varying object categorization requirements while fMRI data were recorded. Response inhibition elicited increased signal change in various brain regions, including medial frontal areas, compared with response selection. BOLD signal in an area within the right angular gyrus was increased when higher-order categorization was mandated. In addition, signal change during response inhibition varied with categorization requirements in the left inferior temporal gyrus (lIT). lIT-mediated response inhibition when inhibiting the response only required lower-order categorization, but lIT mediated both response selection and inhibition when selecting and inhibiting the response required higher-order categorization. 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| source | Journals@Ovid Ovid Autoload; MEDLINE |
| subjects | Adult Biological and medical sciences Brain - physiology Brain Mapping Female Fundamental and applied biological sciences. Psychology Humans Image Processing, Computer-Assisted Inhibition (Psychology) Magnetic Resonance Imaging Male Reaction Time - physiology Semantics Vertebrates: nervous system and sense organs Young Adult |
| title | Semantic processing and response inhibition |
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