How glucocorticoid receptors modulate the activity of other transcription factors: A scope beyond tethering

[Display omitted] ► The pleiotropic glucocorticoid receptor deploys a multitude of mechanisms. ► Glucocorticoids can positively and negatively affect gene transcription. ► Cross-talk of glucocorticoid receptors with other transcription factors is essential. ► Glucocorticoid receptor DNA binding typi...

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Veröffentlicht in:	Molecular and cellular endocrinology 2013-11, Vol.380 (1-2), p.41-54
Hauptverfasser:	Ratman, Dariusz, Vanden Berghe, Wim, Dejager, Lien, Libert, Claude, Tavernier, Jan, Beck, Ilse M., De Bosscher, Karolien
Format:	Artikel
Sprache:	eng
Schlagworte:	adverse effects Animals Chromatin - genetics Chromatin - metabolism Cross-talk DNA Epigenetic Repression gene expression genes Glucocorticoid receptor glucocorticoid receptors Glucocorticoids hormones Humans Protein Kinases - physiology Protein Processing, Post-Translational protein-protein interactions Receptors, Glucocorticoid - physiology Response Elements signal transduction thyroid hormone receptors Transactivation transcription (genetics) Transcription factor transcription factors Transcription Factors - physiology Transcriptional Activation Transrepression
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