Ephrin-B1 Controls the Columnar Distribution of Cortical Pyramidal Neurons by Restricting Their Tangential Migration

Neurons of the cerebral cortex are organized in layers and columns. Unlike laminar patterning, the mechanisms underlying columnar organization remain largely unexplored. Here, we show that ephrin-B1 plays a key role in this process through the control of nonradial steps of migration of pyramidal neu...

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Veröffentlicht in:	Neuron (Cambridge, Mass.) Mass.), 2013-09, Vol.79 (6), p.1123-1135
Hauptverfasser:	Dimidschstein, Jordane, Passante, Lara, Dufour, Audrey, van den Ameele, Jelle, Tiberi, Luca, Hrechdakian, Tatyana, Adams, Ralf, Klein, Rüdiger, Lie, Dieter Chichung, Jossin, Yves, Vanderhaeghen, Pierre
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Animals Animals, Newborn Brain Carrier Proteins - metabolism Cell Adhesion - genetics Cell Cycle Proteins - metabolism Cell Movement - genetics Cerebral Cortex - cytology Electroporation Embryo, Mammalian Ephrin-B1 - deficiency Ephrin-B1 - metabolism Female Gene Expression Regulation, Developmental - genetics Green Fluorescent Proteins - genetics Green Fluorescent Proteins - metabolism Homeodomain Proteins - metabolism Immunoprecipitation In Vitro Techniques Male Mice Mice, Inbred C57BL Mice, Transgenic Migration Nerve Tissue Proteins Neurons Nuclear Proteins - metabolism Pregnancy Pyramidal Cells - physiology Repressor Proteins - metabolism Studies
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