Specific binding of intravenous immunoglobulin products to tau peptide fragments

The effects of intravenous immunoglobulin (IVIG) products are being evaluated in Alzheimer's disease (AD) patients. IVIG contains antibodies to tau protein, the main constituent of neurofibrillary tangles (NFTs). Tau has microtubule binding domain (MBD) repeats which are thought to be necessary...

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Veröffentlicht in:	International immunopharmacology 2014-08, Vol.21 (2), p.279-282
Hauptverfasser:	Smith, Lynnae M., Coffey, Mary P., Loeffler, David A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Antibodies - immunology Antibody binding ELISA Humans Immunoglobulins, Intravenous - immunology Intravenous immunoglobulin IVIG Peptide Fragments - immunology Protein Binding - immunology Tau tau Proteins - immunology
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