Coordination of bacterial proteome with metabolism by cyclic AMP signalling

The cyclic AMP (cAMP)-dependent catabolite repression effect in Escherichia coli is among the most intensely studied regulatory processes in biology. However, the physiological function(s) of cAMP signalling and its molecular triggers remain elusive. Here we use a quantitative physiological approach...

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Veröffentlicht in:	Nature (London) 2013-08, Vol.500 (7462), p.301-306
Hauptverfasser:	You, Conghui, Okano, Hiroyuki, Hui, Sheng, Zhang, Zhongge, Kim, Minsu, Gunderson, Carl W., Wang, Yi-Ping, Lenz, Peter, Yan, Dalai, Hwa, Terence
Format:	Artikel
Sprache:	eng
Schlagworte:	631/326/1320 631/553/1833 Analysis Carbon Cell culture Cyclic adenylic acid Cyclic AMP - metabolism E coli Escherichia coli Escherichia coli - genetics Escherichia coli - metabolism Escherichia coli Proteins - genetics Escherichia coli Proteins - metabolism Gene expression Gene Expression Regulation, Bacterial Glucose Humanities and Social Sciences Lactose Metabolic regulation Metabolism Metabolites Microbiology Models, Biological multidisciplinary Physiological aspects Physiology Proteins Proteome Proteomics Science Signal Transduction
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