Lung type 2 innate lymphoid cells express cysteinyl leukotriene receptor 1, which regulates T sub(H)2 cytokine production

Background: Cysteinyl leukotrienes (CysLTs) contribute to asthma pathogenesis, in part through cysteinyl leukotriene receptor 1 (CysLT1R). Recently discovered lineage-negative type 2 innate lymphoid cells (ILC2s) potently produce IL-5 and IL-13. Objectives: We hypothesized that lung ILC2s might be a...

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Veröffentlicht in:	Journal of allergy and clinical immunology 2013-07, Vol.132 (1), p.205-213
Hauptverfasser:	Doherty, Taylor A, Khorram, Naseem, Lund, Sean, Mehta, Amit Kumar, Croft, Michael, Broide, David H
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternaria
Online-Zugang:	Volltext
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