Sweet liking in patients with Parkinson's disease
Abstract Pleasant tastes and odors are considered phylogenetically old natural rewards and their hedonic evaluation is regarded as a good indicator of the reward system function. The primary aim of the present study was to compare pleasantness ratings of sucrose solutions (1–30%, w/w) and sweet liki...
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| Veröffentlicht in: | Journal of the neurological sciences 2013-06, Vol.329 (1), p.17-22 |
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| creator | Sienkiewicz-Jarosz, Halina Scinska, Anna Swiecicki, Lukasz Lipczynska-Lojkowska, Wanda Kuran, Wlodzimierz Ryglewicz, Danuta Kolaczkowski, Marcin Samochowiec, Jerzy Bienkowski, Przemyslaw |
| description | Abstract Pleasant tastes and odors are considered phylogenetically old natural rewards and their hedonic evaluation is regarded as a good indicator of the reward system function. The primary aim of the present study was to compare pleasantness ratings of sucrose solutions (1–30%, w/w) and sweet liking/disliking status in 20 patients with Parkinson's disease (PD) and in 20 age-matched healthy controls. In addition, basic sensory aspects of gustatory (intensity ratings, electrogustometric thresholds) and olfactory function (identification abilities in the Sniffin' Stick test) were assessed in both groups. The number of odors rated as pleasant, unpleasant, and neutral was also compared. As expected, the PD patients showed a significant impairment in olfactory identification abilities. There were no differences between the PD patients and controls in electrogustometric thresholds. Rated intensity of higher sucrose concentrations did not differ between the groups. The PD patients tended to rate water taste as more intense in comparison with the controls. Pleasantness ratings of sucrose solutions, the proportion of subjects rating 30% sucrose as the most pleasant (sweet likers), and the number of odors rated as pleasant did not differ between the study groups. The present results suggest that PD does not lead to any obvious alterations in pleasantness ratings of chemosensory stimuli. The study requires replication in larger samples. |
| doi_str_mv | 10.1016/j.jns.2013.03.005 |
| format | Article |
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The primary aim of the present study was to compare pleasantness ratings of sucrose solutions (1–30%, w/w) and sweet liking/disliking status in 20 patients with Parkinson's disease (PD) and in 20 age-matched healthy controls. In addition, basic sensory aspects of gustatory (intensity ratings, electrogustometric thresholds) and olfactory function (identification abilities in the Sniffin' Stick test) were assessed in both groups. The number of odors rated as pleasant, unpleasant, and neutral was also compared. As expected, the PD patients showed a significant impairment in olfactory identification abilities. There were no differences between the PD patients and controls in electrogustometric thresholds. Rated intensity of higher sucrose concentrations did not differ between the groups. The PD patients tended to rate water taste as more intense in comparison with the controls. Pleasantness ratings of sucrose solutions, the proportion of subjects rating 30% sucrose as the most pleasant (sweet likers), and the number of odors rated as pleasant did not differ between the study groups. The present results suggest that PD does not lead to any obvious alterations in pleasantness ratings of chemosensory stimuli. The study requires replication in larger samples.</description><identifier>ISSN: 0022-510X</identifier><identifier>EISSN: 1878-5883</identifier><identifier>DOI: 10.1016/j.jns.2013.03.005</identifier><identifier>PMID: 23561981</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Aged ; Analysis of Variance ; Antiparkinson Agents - therapeutic use ; Dose-Response Relationship, Drug ; Female ; Food Preferences - drug effects ; Food Preferences - physiology ; Gustation ; Humans ; Levodopa - therapeutic use ; Male ; Middle Aged ; Neurology ; Olfaction ; Parkinson Disease - drug therapy ; Parkinson Disease - physiopathology ; Parkinson Disease - psychology ; Parkinson's disease ; Reward ; Smell - drug effects ; Smell - physiology ; Sucrose - administration & dosage ; Sweet liking ; Sweetening Agents - administration & dosage ; Taste - drug effects ; Taste - physiology ; Taste Threshold - drug effects ; Taste Threshold - physiology</subject><ispartof>Journal of the neurological sciences, 2013-06, Vol.329 (1), p.17-22</ispartof><rights>2013</rights><rights>Copyright © 2013. Published by Elsevier B.V.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c441t-e6cb5becbe23c486280727daeb3004f46f3230c0798aa5c516d4f584de04421e3</citedby><cites>FETCH-LOGICAL-c441t-e6cb5becbe23c486280727daeb3004f46f3230c0798aa5c516d4f584de04421e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jns.2013.03.005$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23561981$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sienkiewicz-Jarosz, Halina</creatorcontrib><creatorcontrib>Scinska, Anna</creatorcontrib><creatorcontrib>Swiecicki, Lukasz</creatorcontrib><creatorcontrib>Lipczynska-Lojkowska, Wanda</creatorcontrib><creatorcontrib>Kuran, Wlodzimierz</creatorcontrib><creatorcontrib>Ryglewicz, Danuta</creatorcontrib><creatorcontrib>Kolaczkowski, Marcin</creatorcontrib><creatorcontrib>Samochowiec, Jerzy</creatorcontrib><creatorcontrib>Bienkowski, Przemyslaw</creatorcontrib><title>Sweet liking in patients with Parkinson's disease</title><title>Journal of the neurological sciences</title><addtitle>J Neurol Sci</addtitle><description>Abstract Pleasant tastes and odors are considered phylogenetically old natural rewards and their hedonic evaluation is regarded as a good indicator of the reward system function. The primary aim of the present study was to compare pleasantness ratings of sucrose solutions (1–30%, w/w) and sweet liking/disliking status in 20 patients with Parkinson's disease (PD) and in 20 age-matched healthy controls. In addition, basic sensory aspects of gustatory (intensity ratings, electrogustometric thresholds) and olfactory function (identification abilities in the Sniffin' Stick test) were assessed in both groups. The number of odors rated as pleasant, unpleasant, and neutral was also compared. As expected, the PD patients showed a significant impairment in olfactory identification abilities. There were no differences between the PD patients and controls in electrogustometric thresholds. Rated intensity of higher sucrose concentrations did not differ between the groups. The PD patients tended to rate water taste as more intense in comparison with the controls. Pleasantness ratings of sucrose solutions, the proportion of subjects rating 30% sucrose as the most pleasant (sweet likers), and the number of odors rated as pleasant did not differ between the study groups. The present results suggest that PD does not lead to any obvious alterations in pleasantness ratings of chemosensory stimuli. The study requires replication in larger samples.</description><subject>Aged</subject><subject>Analysis of Variance</subject><subject>Antiparkinson Agents - therapeutic use</subject><subject>Dose-Response Relationship, Drug</subject><subject>Female</subject><subject>Food Preferences - drug effects</subject><subject>Food Preferences - physiology</subject><subject>Gustation</subject><subject>Humans</subject><subject>Levodopa - therapeutic use</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Neurology</subject><subject>Olfaction</subject><subject>Parkinson Disease - drug therapy</subject><subject>Parkinson Disease - physiopathology</subject><subject>Parkinson Disease - psychology</subject><subject>Parkinson's disease</subject><subject>Reward</subject><subject>Smell - drug effects</subject><subject>Smell - physiology</subject><subject>Sucrose - administration & dosage</subject><subject>Sweet liking</subject><subject>Sweetening Agents - administration & dosage</subject><subject>Taste - drug effects</subject><subject>Taste - physiology</subject><subject>Taste Threshold - drug effects</subject><subject>Taste Threshold - physiology</subject><issn>0022-510X</issn><issn>1878-5883</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU1rFEEQhhtRzCb6A7zI3PQya1V_TS-CEIJGIaAQBW9NT0-N9mR2Zu2aNeTf28tGDx4UCupQz_senhLiGcIaAe2rYT1MvJaAag1lwDwQK3SNq41z6qFYAUhZG4SvJ-KUeQAA69zmsTiRyljcOFwJvL4lWqox3aTpW5WmaheWRNPC1W1avlefQi4HnqcXXHWJKTA9EY_6MDI9vd9n4su7t58v3tdXHy8_XJxf1VFrXGqysTUtxZakitpZ6aCRTReoVQC617ZXUkGEZuNCMNGg7XRvnO4ItJZI6ky8PPbu8vxjT7z4beJI4xgmmvfs0VhAsGaD_0eVtogWG1dQPKIxz8yZer_LaRvynUfwB6l-8EWqP0j1UAZMyTy_r9-3W-r-JH5bLMDrI0DFx89E2XMsEiN1KVNcfDenf9a_-SsdxzSlGMYbuiMe5n2eimiPnqUHf3346uGpWESitEr9AjLfmlU</recordid><startdate>20130615</startdate><enddate>20130615</enddate><creator>Sienkiewicz-Jarosz, Halina</creator><creator>Scinska, Anna</creator><creator>Swiecicki, Lukasz</creator><creator>Lipczynska-Lojkowska, Wanda</creator><creator>Kuran, Wlodzimierz</creator><creator>Ryglewicz, Danuta</creator><creator>Kolaczkowski, Marcin</creator><creator>Samochowiec, Jerzy</creator><creator>Bienkowski, Przemyslaw</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7QR</scope><scope>7TK</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>20130615</creationdate><title>Sweet liking in patients with Parkinson's disease</title><author>Sienkiewicz-Jarosz, Halina ; Scinska, Anna ; Swiecicki, Lukasz ; Lipczynska-Lojkowska, Wanda ; Kuran, Wlodzimierz ; Ryglewicz, Danuta ; Kolaczkowski, Marcin ; Samochowiec, Jerzy ; Bienkowski, Przemyslaw</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c441t-e6cb5becbe23c486280727daeb3004f46f3230c0798aa5c516d4f584de04421e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Aged</topic><topic>Analysis of Variance</topic><topic>Antiparkinson Agents - therapeutic use</topic><topic>Dose-Response Relationship, Drug</topic><topic>Female</topic><topic>Food Preferences - drug effects</topic><topic>Food Preferences - physiology</topic><topic>Gustation</topic><topic>Humans</topic><topic>Levodopa - therapeutic use</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Neurology</topic><topic>Olfaction</topic><topic>Parkinson Disease - drug therapy</topic><topic>Parkinson Disease - physiopathology</topic><topic>Parkinson Disease - psychology</topic><topic>Parkinson's disease</topic><topic>Reward</topic><topic>Smell - drug effects</topic><topic>Smell - physiology</topic><topic>Sucrose - administration & dosage</topic><topic>Sweet liking</topic><topic>Sweetening Agents - administration & dosage</topic><topic>Taste - drug effects</topic><topic>Taste - physiology</topic><topic>Taste Threshold - drug effects</topic><topic>Taste Threshold - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sienkiewicz-Jarosz, Halina</creatorcontrib><creatorcontrib>Scinska, Anna</creatorcontrib><creatorcontrib>Swiecicki, Lukasz</creatorcontrib><creatorcontrib>Lipczynska-Lojkowska, Wanda</creatorcontrib><creatorcontrib>Kuran, Wlodzimierz</creatorcontrib><creatorcontrib>Ryglewicz, Danuta</creatorcontrib><creatorcontrib>Kolaczkowski, Marcin</creatorcontrib><creatorcontrib>Samochowiec, Jerzy</creatorcontrib><creatorcontrib>Bienkowski, Przemyslaw</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Chemoreception Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Journal of the neurological sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sienkiewicz-Jarosz, Halina</au><au>Scinska, Anna</au><au>Swiecicki, Lukasz</au><au>Lipczynska-Lojkowska, Wanda</au><au>Kuran, Wlodzimierz</au><au>Ryglewicz, Danuta</au><au>Kolaczkowski, Marcin</au><au>Samochowiec, Jerzy</au><au>Bienkowski, Przemyslaw</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sweet liking in patients with Parkinson's disease</atitle><jtitle>Journal of the neurological sciences</jtitle><addtitle>J Neurol Sci</addtitle><date>2013-06-15</date><risdate>2013</risdate><volume>329</volume><issue>1</issue><spage>17</spage><epage>22</epage><pages>17-22</pages><issn>0022-510X</issn><eissn>1878-5883</eissn><abstract>Abstract Pleasant tastes and odors are considered phylogenetically old natural rewards and their hedonic evaluation is regarded as a good indicator of the reward system function. The primary aim of the present study was to compare pleasantness ratings of sucrose solutions (1–30%, w/w) and sweet liking/disliking status in 20 patients with Parkinson's disease (PD) and in 20 age-matched healthy controls. In addition, basic sensory aspects of gustatory (intensity ratings, electrogustometric thresholds) and olfactory function (identification abilities in the Sniffin' Stick test) were assessed in both groups. The number of odors rated as pleasant, unpleasant, and neutral was also compared. As expected, the PD patients showed a significant impairment in olfactory identification abilities. There were no differences between the PD patients and controls in electrogustometric thresholds. Rated intensity of higher sucrose concentrations did not differ between the groups. The PD patients tended to rate water taste as more intense in comparison with the controls. Pleasantness ratings of sucrose solutions, the proportion of subjects rating 30% sucrose as the most pleasant (sweet likers), and the number of odors rated as pleasant did not differ between the study groups. The present results suggest that PD does not lead to any obvious alterations in pleasantness ratings of chemosensory stimuli. The study requires replication in larger samples.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>23561981</pmid><doi>10.1016/j.jns.2013.03.005</doi><tpages>6</tpages></addata></record> |
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| identifier | ISSN: 0022-510X |
| ispartof | Journal of the neurological sciences, 2013-06, Vol.329 (1), p.17-22 |
| issn | 0022-510X 1878-5883 |
| language | eng |
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| subjects | Aged Analysis of Variance Antiparkinson Agents - therapeutic use Dose-Response Relationship, Drug Female Food Preferences - drug effects Food Preferences - physiology Gustation Humans Levodopa - therapeutic use Male Middle Aged Neurology Olfaction Parkinson Disease - drug therapy Parkinson Disease - physiopathology Parkinson Disease - psychology Parkinson's disease Reward Smell - drug effects Smell - physiology Sucrose - administration & dosage Sweet liking Sweetening Agents - administration & dosage Taste - drug effects Taste - physiology Taste Threshold - drug effects Taste Threshold - physiology |
| title | Sweet liking in patients with Parkinson's disease |
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