Comparison of Clinical Outcomes in Nonintubated Patients with Severe Alcohol Withdrawal Syndrome Treated with Continuous-Infusion Sedatives: Dexmedetomidine versus Benzodiazepines

Study Objective To compare efficacy and safety outcomes in nonintubated patients with severe alcohol withdrawal syndrome (AWS) who required a continuous infusion of a benzodiazepine or dexmedetomidine in addition to standard medical therapy for AWS. Design Retrospective cohort study. Setting Two hos...

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Veröffentlicht in:	Pharmacotherapy 2014-09, Vol.34 (9), p.910-917
Hauptverfasser:	Crispo, Angela L., Daley, Mitchell J., Pepin, Jodie L., Harford, Paul H., Brown, Carlos V.R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Alcohol alcohol withdrawal syndrome benzodiazepines Benzodiazepines - adverse effects Benzodiazepines - therapeutic use Cohort Studies critical care dexmedetomidine Dexmedetomidine - adverse effects Dexmedetomidine - therapeutic use Ethanol - adverse effects Female Humans Hypnotics and Sedatives - adverse effects Hypnotics and Sedatives - therapeutic use Infusions, Intravenous Intubation lorazepam Lorazepam - adverse effects Lorazepam - therapeutic use Male Medical treatment midazolam Midazolam - adverse effects Midazolam - therapeutic use Middle Aged Retrospective Studies Severity of Illness Index Substance Withdrawal Syndrome - drug therapy Treatment Outcome
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