Regulation of the mRNA-binding proteins AUF1 by activation of the beta -adrenergic receptor signal transduction pathway

In both cell culture based model systems and in the failing human heart, beta -adrenergic receptors ( beta -AR) undergo agonist-mediated down-regulation. This decrease correlates closely with down-regulation of its mRNA, an effect regulated in part by changes in mRNA stability. Regulation of mRNA st...

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Veröffentlicht in:The Journal of biological chemistry 1996-01, Vol.271 (14), p.8493-8501
Hauptverfasser: Pende, A, Tremmel, K D, DeMaria, C T, Blaxall, B C, Minobe, WA, Sherman, JA, Bisognano, J D, Bristow, M R, Brewer, G, Port, J D
Format: Artikel
Sprache:eng
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