Unprecedented conformational flexibility revealed in the ligand-binding domains of the Bovicola ovis ecdysone receptor (EcR) and ultraspiracle (USP) subunits

The heterodimeric ligand‐binding region of the Bovicola ovis ecdysone receptor has been crystallized either in the presence of an ecdysteroid or a synthetic methylene lactam insecticide. Two X‐ray crystallographic structures, determined at 2.7 Å resolution, show that the ligand‐binding domains of bo...

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