Infectivity of Chimeric Human T-Cell Leukemia Virus Type I Molecular Clones Assessed by Naked DNA Inoculation

Two human T-cell leukemia virus type I (HTLV-I) molecular clones, K30p and K34p were derived from HTLV-I-infected rabbit cell lines. K30p and K34p differ by 18 bp with changes in the long terminal repeats (LTRs) as well as in the gag, pol, and rex but not tax or env gene products. Cells transfected...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1996-06, Vol.93 (13), p.6653-6658
Hauptverfasser:	Zhao, T. M., Robinson, M. A., Bowers, F. S., Kindt, T. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Animals Base Sequence Cell Line Cell lines Cells Cellular biology Chimeras Cloning, Molecular Deoxyribonucleic acid DNA DNA, Viral - administration & dosage Genes Genes, gag Genes, pol Genes, pX Genomics Human T lymphotropic virus 1 Human T-lymphotropic virus 1 - genetics Human T-lymphotropic virus 1 - pathogenicity Humans Immunity (Disease) Infections Inoculation Leukemia Molecular Sequence Data Polymerase Chain Reaction Proviruses Rabbits Repetitive Sequences, Nucleic Acid Transfection Virulence - genetics Virus Replication Viruses
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