Synthesis and characterization of some acyl thiourea derivatives of chitosan and their biocidal activities

Three acyl derivatives of chitosan (CS) with different side chains were synthesized and their structures were characterized. Their swelling behavior was investigated. The antifungal behavior of these chitosan derivatives was investigated in vitro on the mycelial growth, sporulation and germination o...

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Veröffentlicht in:International journal of biological macromolecules 2014-09, Vol.70, p.199-207
Hauptverfasser: Elkholy, Said S., Salem, Hend A., Eweis, Mohamed, Elsabee, Maher Z.
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container_title International journal of biological macromolecules
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creator Elkholy, Said S.
Salem, Hend A.
Eweis, Mohamed
Elsabee, Maher Z.
description Three acyl derivatives of chitosan (CS) with different side chains were synthesized and their structures were characterized. Their swelling behavior was investigated. The antifungal behavior of these chitosan derivatives was investigated in vitro on the mycelial growth, sporulation and germination of conidia or sclerotia of the sugar-beet pathogens, Rhizoctonia solani K”uhn (AG2-2) and Sclerotium rolfsii Sacc. All the prepared derivatives had a significant inhibiting effect on the different stages of development on the germination of conidia or sclerotia of all the investigated fungi. In the absence of chitosan and its derivative, R. solani exhibited the fastest growth of the fungi studied.
doi_str_mv 10.1016/j.ijbiomac.2014.05.068
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subjects Antifungal activity 1
Antifungal Agents - chemistry
Antifungal Agents - pharmacology
Characterization
Chitosan - chemical synthesis
Chitosan - chemistry
Chitosan thiourea
Disinfectants - chemistry
Disinfectants - pharmacology
Microbial Sensitivity Tests
Spectroscopy, Fourier Transform Infrared
Swelling behavior
Thermogravimetry
Thiourea - chemistry
X-Ray Diffraction
title Synthesis and characterization of some acyl thiourea derivatives of chitosan and their biocidal activities
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