Exposure of Residues in the Cyclic Nucleotide–Gated Channel Pore: P Region Structure and Function in Gating

In voltage-gated ion channels and in the homologous cyclic nucleotide–gated (CNG) channels, the loop between the S5 and S6 transmembrane segments (P region) is thought to form the lining of the pore. To investigate the structure and the role in gating of the P region of the bovine retinal CNG channe...

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Veröffentlicht in:Neuron (Cambridge, Mass.) Mass.), 1996, Vol.16 (1), p.141-149
Hauptverfasser: Sun, Zhong-Ping, Akabas, Myles H, Goulding, Evan H, Karlin, Arthur, Siegelbaum, Steven A
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Sprache:eng
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