Involvement of IL-17A in preventing the development of deep-seated candidiasis from oropharyngeal infection

In this study we show that corticosteroid-treated Il17a−/− mice develop invasive candidiasis from oropharyngeal infection whereas WT mice do not. By using an established murine model of oral candidiasis we document the spatial and temporal progression of fungal infection. The histological analysis o...

Ausführliche Beschreibung