Slight Increases in the Disease Activity Index and Platelet Count Imply the Presence of Active Intestinal Lesions in C-reactive Protein-negative Crohn's Disease Patients

Objective Although the serum C-reactive protein (CRP) level may, to some extent, predict the disease activity in patients with Crohn's disease (CD), it is not always elevated during periods of disease activity. This study aimed to identify factors predicting the presence of active intestinal le...

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Veröffentlicht in:Internal Medicine 2014, Vol.53(17), pp.1905-1911
Hauptverfasser: Nakarai, Asuka, Kato, Jun, Hiraoka, Sakiko, Inokuchi, Toshihiro, Takei, Daisuke, Morito, Yuki, Akita, Mitsuhiro, Takahashi, Sakuma, Hori, Keisuke, Harada, Keita, Okada, Hiroyuki, Yamamoto, Kazuhide
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Sprache:eng
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Zusammenfassung:Objective Although the serum C-reactive protein (CRP) level may, to some extent, predict the disease activity in patients with Crohn's disease (CD), it is not always elevated during periods of disease activity. This study aimed to identify factors predicting the presence of active intestinal lesions in CD patients without an elevated CRP level. Methods CD patients in whom the presence or absence of active intestinal lesions was evaluated using endoscopic and/or radiologic modalities were divided into two groups based on a negative (
ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.53.2627