The Sterile 20-Like Kinase Tao Controls Tissue Homeostasis by Regulating the Hippo Pathway in Drosophila Adult Midgut

The proliferation and differentiation of adult stem cells must be tightly controlled in order to maintain resident tissue homeostasis. Dysfunction of stem cells is implicated in many human diseases, including cancer. However, the regulation of stem cell proliferation and differentiation is not fully...

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Veröffentlicht in:	Journal of genetics and genomics 2014-08, Vol.41 (8), p.429-438
Hauptverfasser:	Huang, Xudong, Shi, Lai, Cao, Jun, He, Fangfei, Li, Renling, Zhang, Yan, Miao, Shuang, Jin, Longjin, Qu, Jia, Li, Zhouhua, Lin, Xinhua
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Proliferation Drosophila Drosophila melanogaster - cytology Drosophila melanogaster - metabolism Drosophila Proteins - deficiency Drosophila Proteins - metabolism Female Hippo Homeostasis Intestinal Mucosa - metabolism Intestines - cytology Intracellular Signaling Peptides and Proteins - metabolism Janus Kinases - metabolism Janus激酶 Midgut Nuclear Proteins - metabolism Protein-Serine-Threonine Kinases - deficiency Protein-Serine-Threonine Kinases - metabolism Signal Transduction STAT Transcription Factors - metabolism Stem cell Stem Cells - cytology Tao Tissue homeostasis Trans-Activators - metabolism 平衡果蝇河马稳态控制组织肠道通路
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