A mouse model for studying cone photoreceptor pathologies

Due to the low abundance of cone photoreceptors in the mouse retina and the scarcity of alternative animal models, little is known about mechanisms of cone degeneration. Nrl knockout mice develop exclusively the cone-type of photoreceptors. However, the cone photoreceptor layer in Nrl(-/-) mice disp...

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Veröffentlicht in:	Investigative ophthalmology & visual science 2014-07, Vol.55 (8), p.5304-5313
Hauptverfasser:	Samardzija, Marijana, Caprara, Christian, Heynen, Severin R, Willcox DeParis, Sarah, Meneau, Isabelle, Traber, Ghislaine, Agca, Cavit, von Lintig, Johannes, Grimm, Christian
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chromatography, High Pressure Liquid cis-trans-Isomerases - metabolism Disease Models, Animal Electroretinography Mice, Inbred C57BL Mice, Knockout Microscopy, Electron Retina - metabolism Retinal Cone Photoreceptor Cells - physiology Retinal Degeneration - pathology Retinal Degeneration - physiopathology Retinaldehyde - deficiency
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