Influence of exercise intensity on systemic oxidative stress and antioxidant capacity
Summary The aim of the current study was to examine the influence of exercise intensity on systemic oxidative stress (OS) and endogenous antioxidant capacity. Non‐smoking, sedentary healthy adult males (n = 14) participated in two exercise sessions using an electronically braked cycle ergometer. The...
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| Veröffentlicht in: | Clinical physiology and functional imaging 2014-09, Vol.34 (5), p.377-383 |
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| creator | Parker, Lewan McGuckin, Teneale A. Leicht, Anthony S. |
| description | Summary
The aim of the current study was to examine the influence of exercise intensity on systemic oxidative stress (OS) and endogenous antioxidant capacity. Non‐smoking, sedentary healthy adult males (n = 14) participated in two exercise sessions using an electronically braked cycle ergometer. The first session consisted of a graded exercise test to determine maximal power output and oxygen consumption (VO2max). One week later, participants undertook 5‐min cycling bouts at 40%, 55%, 70%, 85% and 100% of VO2max, with passive 12‐min rest between stages. Measures of systemic OS reactive oxygen metabolites (dROM), biological antioxidant potential (BAP), heart rate (HR), VO2, blood lactate and rating of perceived exertion were assessed at rest and immediately following each exercise stage. Significant (P |
| doi_str_mv | 10.1111/cpf.12108 |
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The aim of the current study was to examine the influence of exercise intensity on systemic oxidative stress (OS) and endogenous antioxidant capacity. Non‐smoking, sedentary healthy adult males (n = 14) participated in two exercise sessions using an electronically braked cycle ergometer. The first session consisted of a graded exercise test to determine maximal power output and oxygen consumption (VO2max). One week later, participants undertook 5‐min cycling bouts at 40%, 55%, 70%, 85% and 100% of VO2max, with passive 12‐min rest between stages. Measures of systemic OS reactive oxygen metabolites (dROM), biological antioxidant potential (BAP), heart rate (HR), VO2, blood lactate and rating of perceived exertion were assessed at rest and immediately following each exercise stage. Significant (P<0·05) differences between exercise bouts were examined via repeated measures ANOVA and post hoc pairwise comparisons with Bonferroni correction. Increasing exercise intensity significantly augmented HR (P<0·001), VO2 (P<0·001), blood lactate (P<0·001) and perceived exertion (P<0·001) with no significant effect on dROM levels compared with resting values. In contrast, increasing exercise intensity resulted in significantly (P<0·01) greater BAP at 70% (2427 ± 106), 85% (2625 ± 121) and 100% (2651 ± 92) of VO2max compared with resting levels (2105 ± 57 μmol Fe2+/L). The current results indicate that brief, moderate‐to‐high‐intensity exercise significantly elevates endogenous antioxidant defences, possibly to counteract increased levels of exercise‐induced reactive oxygen species. Regular moderate‐to‐high‐intensity exercise may protect against chronic OS associated diseases via activation, and subsequent upregulation of the endogenous antioxidant defence system.]]></description><identifier>ISSN: 1475-0961</identifier><identifier>EISSN: 1475-097X</identifier><identifier>DOI: 10.1111/cpf.12108</identifier><identifier>PMID: 24283399</identifier><identifier>CODEN: CPFICA</identifier><language>eng</language><publisher>England: Blackwell Publishing Ltd</publisher><subject>Antioxidants - metabolism ; Bicycling ; Biomarkers - blood ; chronic disease ; cycle ; Exercise ; Heart Rate ; Humans ; hydroperoxide ; Lactic Acid - blood ; Male ; Muscle Contraction ; Muscle Strength ; Muscle, Skeletal - metabolism ; Oxidative Stress ; Oxygen Consumption ; physical activity ; reactive oxygen species ; Reactive Oxygen Species - metabolism ; redox ; Sedentary Lifestyle ; Time Factors ; Up-Regulation ; Young Adult</subject><ispartof>Clinical physiology and functional imaging, 2014-09, Vol.34 (5), p.377-383</ispartof><rights>2013 Scandinavian Society of Clinical Physiology and Nuclear Medicine. Published by John Wiley & Sons Ltd</rights><rights>2013 Scandinavian Society of Clinical Physiology and Nuclear Medicine. Published by John Wiley & Sons Ltd.</rights><rights>Copyright © 2014 Scandinavian Society of Clinical Physiology and Nuclear Medicine</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4908-a42a6b8a39862c39338682f6d14a8dee66aace4786737a9971d2947485e80d2a3</citedby><cites>FETCH-LOGICAL-c4908-a42a6b8a39862c39338682f6d14a8dee66aace4786737a9971d2947485e80d2a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fcpf.12108$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fcpf.12108$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24283399$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Parker, Lewan</creatorcontrib><creatorcontrib>McGuckin, Teneale A.</creatorcontrib><creatorcontrib>Leicht, Anthony S.</creatorcontrib><title>Influence of exercise intensity on systemic oxidative stress and antioxidant capacity</title><title>Clinical physiology and functional imaging</title><addtitle>Clin Physiol Funct Imaging</addtitle><description><![CDATA[Summary
The aim of the current study was to examine the influence of exercise intensity on systemic oxidative stress (OS) and endogenous antioxidant capacity. Non‐smoking, sedentary healthy adult males (n = 14) participated in two exercise sessions using an electronically braked cycle ergometer. The first session consisted of a graded exercise test to determine maximal power output and oxygen consumption (VO2max). One week later, participants undertook 5‐min cycling bouts at 40%, 55%, 70%, 85% and 100% of VO2max, with passive 12‐min rest between stages. Measures of systemic OS reactive oxygen metabolites (dROM), biological antioxidant potential (BAP), heart rate (HR), VO2, blood lactate and rating of perceived exertion were assessed at rest and immediately following each exercise stage. Significant (P<0·05) differences between exercise bouts were examined via repeated measures ANOVA and post hoc pairwise comparisons with Bonferroni correction. Increasing exercise intensity significantly augmented HR (P<0·001), VO2 (P<0·001), blood lactate (P<0·001) and perceived exertion (P<0·001) with no significant effect on dROM levels compared with resting values. In contrast, increasing exercise intensity resulted in significantly (P<0·01) greater BAP at 70% (2427 ± 106), 85% (2625 ± 121) and 100% (2651 ± 92) of VO2max compared with resting levels (2105 ± 57 μmol Fe2+/L). The current results indicate that brief, moderate‐to‐high‐intensity exercise significantly elevates endogenous antioxidant defences, possibly to counteract increased levels of exercise‐induced reactive oxygen species. Regular moderate‐to‐high‐intensity exercise may protect against chronic OS associated diseases via activation, and subsequent upregulation of the endogenous antioxidant defence system.]]></description><subject>Antioxidants - metabolism</subject><subject>Bicycling</subject><subject>Biomarkers - blood</subject><subject>chronic disease</subject><subject>cycle</subject><subject>Exercise</subject><subject>Heart Rate</subject><subject>Humans</subject><subject>hydroperoxide</subject><subject>Lactic Acid - blood</subject><subject>Male</subject><subject>Muscle Contraction</subject><subject>Muscle Strength</subject><subject>Muscle, Skeletal - metabolism</subject><subject>Oxidative Stress</subject><subject>Oxygen Consumption</subject><subject>physical activity</subject><subject>reactive oxygen species</subject><subject>Reactive Oxygen Species - metabolism</subject><subject>redox</subject><subject>Sedentary Lifestyle</subject><subject>Time Factors</subject><subject>Up-Regulation</subject><subject>Young Adult</subject><issn>1475-0961</issn><issn>1475-097X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kF1LHDEUhkNpqXbtRf-ABLzRi9F8TT4u66KuIFVE0bsQM2cgOpvZJjPt7r9v1tW9EBo4JJDnfTk8CP2g5JiWc-IX7TFllOhPaJcKVVfEqMfP27ekO-hbzs-EUMWF-op2mGCac2N20f1lbLsRogfctxiWkHzIgEMcIOYwrHAfcV7lAebB434ZGjeEP4DzkCBn7GJTZgivH3HA3i2cL6k99KV1XYbvb_cE3Z-f3U1n1dX1xeX051XlhSG6coI5-aQdN1oyzw3nWmrWyoYKpxsAKZ3zIJSWiitnjKINM0IJXYMmDXN8gg43vYvU_x4hD3YesoeucxH6MVta17pmVBNZ0IMP6HM_pli2W1O10ZooU6ijDeVTn3OC1i5SmLu0spTYtWtbXNtX14Xdf2scn-bQbMl3uQU42QB_Qwer_zfZ6c35e2W1SYRifLlNuPRi1wpq-_DrwrLbW07p6cye8n-ZJZbA</recordid><startdate>201409</startdate><enddate>201409</enddate><creator>Parker, Lewan</creator><creator>McGuckin, Teneale A.</creator><creator>Leicht, Anthony S.</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7TS</scope><scope>7U5</scope><scope>8FD</scope><scope>K9.</scope><scope>L7M</scope><scope>7X8</scope></search><sort><creationdate>201409</creationdate><title>Influence of exercise intensity on systemic oxidative stress and antioxidant capacity</title><author>Parker, Lewan ; McGuckin, Teneale A. ; Leicht, Anthony S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4908-a42a6b8a39862c39338682f6d14a8dee66aace4786737a9971d2947485e80d2a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Antioxidants - metabolism</topic><topic>Bicycling</topic><topic>Biomarkers - blood</topic><topic>chronic disease</topic><topic>cycle</topic><topic>Exercise</topic><topic>Heart Rate</topic><topic>Humans</topic><topic>hydroperoxide</topic><topic>Lactic Acid - blood</topic><topic>Male</topic><topic>Muscle Contraction</topic><topic>Muscle Strength</topic><topic>Muscle, Skeletal - metabolism</topic><topic>Oxidative Stress</topic><topic>Oxygen Consumption</topic><topic>physical activity</topic><topic>reactive oxygen species</topic><topic>Reactive Oxygen Species - metabolism</topic><topic>redox</topic><topic>Sedentary Lifestyle</topic><topic>Time Factors</topic><topic>Up-Regulation</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Parker, Lewan</creatorcontrib><creatorcontrib>McGuckin, Teneale A.</creatorcontrib><creatorcontrib>Leicht, Anthony S.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Physical Education Index</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical physiology and functional imaging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Parker, Lewan</au><au>McGuckin, Teneale A.</au><au>Leicht, Anthony S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Influence of exercise intensity on systemic oxidative stress and antioxidant capacity</atitle><jtitle>Clinical physiology and functional imaging</jtitle><addtitle>Clin Physiol Funct Imaging</addtitle><date>2014-09</date><risdate>2014</risdate><volume>34</volume><issue>5</issue><spage>377</spage><epage>383</epage><pages>377-383</pages><issn>1475-0961</issn><eissn>1475-097X</eissn><coden>CPFICA</coden><abstract><![CDATA[Summary
The aim of the current study was to examine the influence of exercise intensity on systemic oxidative stress (OS) and endogenous antioxidant capacity. Non‐smoking, sedentary healthy adult males (n = 14) participated in two exercise sessions using an electronically braked cycle ergometer. The first session consisted of a graded exercise test to determine maximal power output and oxygen consumption (VO2max). One week later, participants undertook 5‐min cycling bouts at 40%, 55%, 70%, 85% and 100% of VO2max, with passive 12‐min rest between stages. Measures of systemic OS reactive oxygen metabolites (dROM), biological antioxidant potential (BAP), heart rate (HR), VO2, blood lactate and rating of perceived exertion were assessed at rest and immediately following each exercise stage. Significant (P<0·05) differences between exercise bouts were examined via repeated measures ANOVA and post hoc pairwise comparisons with Bonferroni correction. Increasing exercise intensity significantly augmented HR (P<0·001), VO2 (P<0·001), blood lactate (P<0·001) and perceived exertion (P<0·001) with no significant effect on dROM levels compared with resting values. In contrast, increasing exercise intensity resulted in significantly (P<0·01) greater BAP at 70% (2427 ± 106), 85% (2625 ± 121) and 100% (2651 ± 92) of VO2max compared with resting levels (2105 ± 57 μmol Fe2+/L). The current results indicate that brief, moderate‐to‐high‐intensity exercise significantly elevates endogenous antioxidant defences, possibly to counteract increased levels of exercise‐induced reactive oxygen species. Regular moderate‐to‐high‐intensity exercise may protect against chronic OS associated diseases via activation, and subsequent upregulation of the endogenous antioxidant defence system.]]></abstract><cop>England</cop><pub>Blackwell Publishing Ltd</pub><pmid>24283399</pmid><doi>10.1111/cpf.12108</doi><tpages>7</tpages></addata></record> |
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| subjects | Antioxidants - metabolism Bicycling Biomarkers - blood chronic disease cycle Exercise Heart Rate Humans hydroperoxide Lactic Acid - blood Male Muscle Contraction Muscle Strength Muscle, Skeletal - metabolism Oxidative Stress Oxygen Consumption physical activity reactive oxygen species Reactive Oxygen Species - metabolism redox Sedentary Lifestyle Time Factors Up-Regulation Young Adult |
| title | Influence of exercise intensity on systemic oxidative stress and antioxidant capacity |
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