Flow cytometric immunophenotypic analysis of systemic mastocytosis involving bone marrow

Mast cells of systemic mastocytosis (SM) have aberrant immunophenotypes that are useful for their detection by flow cytometry immunophenotyping. To assess the usefulness of CD2, CD25, and other antigens for establishing the diagnosis of SM in bone marrow using flow cytometry immunophenotyping. We st...

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Veröffentlicht in:	Archives of pathology & laboratory medicine (1976) 2014-09, Vol.138 (9), p.1210-1214
Hauptverfasser:	Jabbar, Kausar J, Medeiros, L Jeffrey, Wang, Sa A, Miranda, Roberto N, Johnson, Malisha R, Verstovsek, Srdan, Jorgensen, Jeffrey L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Analysis Antibodies Antigens Antigens, CD - metabolism Antigens, Differentiation, T-Lymphocyte - metabolism Biopsy Blood diseases Bone marrow Bone Marrow - immunology Bone Marrow - pathology CD2 Antigens - metabolism CD59 Antigens - metabolism Cytoplasm Female Flow cytometry Flow Cytometry - methods Fluorescein Fluorescein-5-isothiocyanate Humans Immunohistochemistry Immunophenotyping - methods Interleukin-2 Receptor alpha Subunit - metabolism Lectins, C-Type - metabolism Leukemia Male Mast Cells - immunology Mast Cells - pathology Mastocytosis Mastocytosis, Systemic - diagnosis Mastocytosis, Systemic - immunology Mastocytosis, Systemic - pathology Medical research Middle Aged Patients Phycoerythrin Receptors, Complement 3b - metabolism Retrospective Studies Sensitivity and Specificity Software Tetraspanin 30 - metabolism
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