Mechanisms Involved in the Induction of Human Endothelial Cell Necrosis

The effects of the inflammatory mediators lipopolysaccharide (LPS) and tumor necrosis factor-α (TNF) and unstimulated and activated neutrophils (PMNs) on endothelial cell (EC) necrosis were studied using the cultured human EC line (ECV-304) and human PMNsin vitro.LPS and TNF alone or their combinati...

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Veröffentlicht in:	Cellular immunology 1996-02, Vol.168 (1), p.91-99
Hauptverfasser:	Wang, Jiang Huai, Redmond, H.Paul, Watson, R.William G., Duggan, Susan, McCarthy, Julie, Barry, Mary, Bouchier-Hayes, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aprotinin - pharmacology Cell Adhesion - drug effects Cell Line Drug Synergism Endothelium, Vascular - drug effects Endothelium, Vascular - pathology Humans Intercellular Adhesion Molecule-1 - biosynthesis Lipopolysaccharides - toxicity Necrosis Neutrophil Activation Tumor Necrosis Factor-alpha - toxicity Umbilical Veins
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