High avidity monoclonal antibody to imidazole ring-opened 7-methylguanine

A hybridoma (K1A8) secreting a high affinity antibody to imidazole ring-opened 7-methylguanine (N5-methyl-N5-formyl-2, 5,6-triamino-4-hydroxypyrimidine) was obtained from spleen cells of a mouse immunized with a conjugate of keyhole-limpet hemocyanin and imidazole ring-opened 7-methylguanylic acid (...

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Veröffentlicht in:	Carcinogenesis (New York) 1989-05, Vol.10 (5), p.927-931
Hauptverfasser:	Stein, Abraham M., Gratzner, Howard G., Stein, Jeanne H., McCabe, Mead M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkylating Agents - pharmacology Alkylation Animals Antibodies, Monoclonal Antigen-Antibody Complex - analysis Biological and medical sciences Cell physiology Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes Cells, Cultured DNA - drug effects Enzyme-Linked Immunosorbent Assay Epitopes - analysis Fundamental and applied biological sciences. Psychology Guanine - analogs & derivatives Guanine - immunology Haptens Hybridomas - immunology Lymphocytes - immunology Methylnitronitrosoguanidine - pharmacology Mice Molecular and cellular biology Pyrimidines - immunology Sulfuric Acid Esters - pharmacology
Online-Zugang:	Volltext
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