Multiple intracellular pathways induce expression of a zinc-finger encoding gene (EGR1): Relationship to activation of the Na/H exchanger

Intracellular pathways that rapidly stimulate the expression of a mitogeninducible, zinc‐finger encoding gene, EGR1 (Sukhatme et al., Cell 53:37–43), have been characterized in two human fibroblasts strains (WI‐38 and HSWP). Serum and epidermal growth factor (EGF) were each found to strongly stimula...

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Veröffentlicht in:	Journal of cellular physiology 1989-05, Vol.139 (2), p.262-268
Hauptverfasser:	Jamieson Jr, Gordon A., Mayforth Jr, Ruth D., Villereal, Mitchel L., Sukhatme, Vikas P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Carrier Proteins - metabolism Cell physiology Cells, Cultured DNA-Binding Proteins - genetics Fundamental and applied biological sciences. Psychology Gene Expression Regulation Humans Immunoblotting Metalloproteins - genetics Molecular and cellular biology Protein Kinase C - metabolism Responses to growth factors, tumor promotors, other factors RNA, Messenger - isolation & purification Sodium-Hydrogen Exchangers Tetradecanoylphorbol Acetate - pharmacology Transcription, Genetic
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