Aluminium-induced bone disease in uremic rats: effect of deferoxamine

We have previously established a rat model of chronic uremia, which is suitable to investigate the effect of various treatment modalities on renal osteodystrophy [1]. After four months subsequent to 5/6 nephrectomy, some animals were treated by gavage for 9 weeks with tap water (controls), or with a...

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Veröffentlicht in:	Bioscience reports 1996-02, Vol.16 (1), p.49-63
Hauptverfasser:	Jablonski, G, Klem, K H, Danielsen, C C, Mosekilde, L, Gordeladze, J O
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenylyl Cyclases - metabolism Aluminum - blood Aluminum - metabolism Aluminum - toxicity Animals Biomechanical Phenomena Bone and Bones - drug effects Bone and Bones - metabolism Bone and Bones - pathology Bone Diseases - drug therapy Bone Diseases - etiology Bone Diseases - prevention & control Bone Remodeling - drug effects Chronic Kidney Disease-Mineral and Bone Disorder - drug therapy Chronic Kidney Disease-Mineral and Bone Disorder - etiology Chronic Kidney Disease-Mineral and Bone Disorder - prevention & control Deferoxamine - pharmacology Female Osteomalacia - drug therapy Osteomalacia - etiology Osteomalacia - prevention & control Parathyroid Hormone - pharmacology Rats Rats, Wistar Siderophores - pharmacology Type C Phospholipases - metabolism Uremia - complications
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