Cryptosporidium parvum infection in T-cell receptor (TCR)-alpha- and TCR-delta-deficient mice

Mice deficient in either alpha-beta or gamma- delta T cells were more susceptible to infection with the protozoan parasite Cryptosporidium parvum than were control mice. Both neonatal and adult alpha-beta-T-cell- deficient mice developed chronic infection. gamma-delta-T-cell-deficient neonatal mice...

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Veröffentlicht in:	Infection and Immunity 1996-05, Vol.64 (5), p.1854-1857
Hauptverfasser:	Waters, W.R. (Metabolic Diseases and Immunology Research Unit, National Animal Disease Center, USDA, ARS, Ames, IA.), Harp, J.A
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of the immune response. Humoral and cellular immunity Animals Animals, Newborn Biological and medical sciences CD4-Positive T-Lymphocytes - immunology Chronic Disease Cryptosporidiosis - immunology Cryptosporidiosis - pathology CRYPTOSPORIDIUM PARVUM Female Fundamental and applied biological sciences. Psychology Fundamental immunology Immunobiology Male Mice Mice, Inbred C57BL Mice, Mutant Strains Organs and cells involved in the immune response Receptors, Antigen, T-Cell, alpha-beta - deficiency Receptors, Antigen, T-Cell, alpha-beta - genetics Receptors, Antigen, T-Cell, gamma-delta - deficiency Receptors, Antigen, T-Cell, gamma-delta - genetics
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