Synthesis of a radiolabeled cyclodepsipeptide [3H-methyl]PF1022A

For receptor binding studies and the elucidation of the mode of action of the potent anthelmintic compound PF1022A a tritium labeled compound with very high specific activity was necessary. Tritium was introduced into the compound by methylation of the [bis‐N‐demethyl]precursor of PF1022A (PF1022‐21...

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Veröffentlicht in:	Journal of labelled compounds & radiopharmaceuticals 1996-01, Vol.38 (1), p.61-69
Hauptverfasser:	Pleiss, U., Harder, A., Turberg, A., Londershausen, M., Iinuma, K., Mencke, N., Jeschke, P., Bonse, G.
Format:	Artikel
Sprache:	eng
Schlagworte:	[bis-N-methyl-3H]PF1022A anthelmintic Antibiotics. Antiinfectious agents. Antiparasitic agents Antiparasitic agents Biological and medical sciences Chemistry cyclodepsipeptide Exact sciences and technology Medical sciences mode of action Organic chemistry Peptides PF1022A Pharmacology. Drug treatments Preparations and properties
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