Aortic valve and aortic root features in CT angiography in patients considered for aortic valve repair

Abstract Background The underlying mechanism of aortic regurgitation and aortic valve and root characteristics are associated with the durability of surgical repair. Objective We investigated whether multidetector CT (MDCT) identifies the characteristics of the aortic valve and root that may be asso...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of cardiovascular computed tomography 2014-07, Vol.8 (4), p.299-306
Hauptverfasser: Regeer, Madelien V., MD, Kamperidis, Vasileios, MD, MSc, Versteegh, Michel I.M., MD, Klautz, Robert J.M., MD, PhD, Scholte, Arthur J.H.A., MD, PhD, Bax, Jeroen J., MD, PhD, Schalij, Martin J., MD, PhD, Marsan, Nina Ajmone, MD, PhD, Delgado, Victoria, MD, PhD
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 306
container_issue 4
container_start_page 299
container_title Journal of cardiovascular computed tomography
container_volume 8
creator Regeer, Madelien V., MD
Kamperidis, Vasileios, MD, MSc
Versteegh, Michel I.M., MD
Klautz, Robert J.M., MD, PhD
Scholte, Arthur J.H.A., MD, PhD
Bax, Jeroen J., MD, PhD
Schalij, Martin J., MD, PhD
Marsan, Nina Ajmone, MD, PhD
Delgado, Victoria, MD, PhD
description Abstract Background The underlying mechanism of aortic regurgitation and aortic valve and root characteristics are associated with the durability of surgical repair. Objective We investigated whether multidetector CT (MDCT) identifies the characteristics of the aortic valve and root that may be associated with the ability to perform successful surgical repair. Methods Sixty-one patients with aortic regurgitation and/or aortic root pathology who were evaluated for aortic valve or root repair and underwent clinically indicated gated or nongated MDCT of the aortic valve and aortic root were included in the present analysis. Patients with endocarditis were excluded. MDCT data of aortic valve anatomy and calcification and thoracic aorta dimensions were analyzed. Results The aortic valve and root was successfully repaired in 36 patients (55 ± 13 years; 61% male; median EuroSCORE II, 3.8%) whereas in 25 patients (56 ± 15 years; 52% male; median EuroSCORE II, 2.5%) repair was not attempted (n = 20) or valve repair was converted to aortic valve replacement during surgery (n = 5). In patients in whom repair was considered not possible or failed, there was a higher percentage of bicuspid aortic valves (48% vs 17%; P  = .019), more severe commissural calcification, and more severe annular calcification. Conclusion The degree of commissural and annular calcification of the aortic valve determined by MDCT is inversely related to the ability to perform surgical valve repair instead of replacement. Similarly, bicuspid valve anatomy predicts failure to perform repair.
doi_str_mv 10.1016/j.jcct.2014.06.008
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1556283934</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S1934592514001622</els_id><sourcerecordid>1556283934</sourcerecordid><originalsourceid>FETCH-LOGICAL-c411t-af9a30347274b3435672fde4309fd398c12b37e507ab909b29c6bc45f522d9a23</originalsourceid><addsrcrecordid>eNp9kUtr3TAQRkVpaR7tH-iieNmNHT1tC0ogXNImEOiiKXQnZGmUyPG1XMm-cP99ZZx0kUVXEqNvzqAzCH0iuCKY1Bd91RszVxQTXuG6wrh9g05J29RlW5Pfb_NdMl4KScUJOkupx1g0BLfv0QkVRBBJ6SlyVyHO3hQHPRyg0KMt9FaIIcyFAz0vEVLhx2J3n58ffHiIeno8rpVJzx7GORUmjMlbiGALF-ILYUNGmLSPH9A7p4cEH5_Pc_Tr2_X97qa8-_H9dnd1VxpOyFxqJzXDjDe04R3jTNQNdRY4w9JZJltDaMcaELjRncSyo9LUneHCCUqt1JSdoy8bd4rhzwJpVnufDAyDHiEsSREhatqy7CVH6RY1MaQUwakp-r2OR0WwWv2qXq1-1epX4Vplv7np8zN_6fZg_7W8CM2Br1sA8i8PHqJKJksyYH2EDLPB_59_-ardDH70Rg9PcITUhyWO2Z8iKlGF1c91w-uCCceZmOf_BU0VoQY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1556283934</pqid></control><display><type>article</type><title>Aortic valve and aortic root features in CT angiography in patients considered for aortic valve repair</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><creator>Regeer, Madelien V., MD ; Kamperidis, Vasileios, MD, MSc ; Versteegh, Michel I.M., MD ; Klautz, Robert J.M., MD, PhD ; Scholte, Arthur J.H.A., MD, PhD ; Bax, Jeroen J., MD, PhD ; Schalij, Martin J., MD, PhD ; Marsan, Nina Ajmone, MD, PhD ; Delgado, Victoria, MD, PhD</creator><creatorcontrib>Regeer, Madelien V., MD ; Kamperidis, Vasileios, MD, MSc ; Versteegh, Michel I.M., MD ; Klautz, Robert J.M., MD, PhD ; Scholte, Arthur J.H.A., MD, PhD ; Bax, Jeroen J., MD, PhD ; Schalij, Martin J., MD, PhD ; Marsan, Nina Ajmone, MD, PhD ; Delgado, Victoria, MD, PhD</creatorcontrib><description>Abstract Background The underlying mechanism of aortic regurgitation and aortic valve and root characteristics are associated with the durability of surgical repair. Objective We investigated whether multidetector CT (MDCT) identifies the characteristics of the aortic valve and root that may be associated with the ability to perform successful surgical repair. Methods Sixty-one patients with aortic regurgitation and/or aortic root pathology who were evaluated for aortic valve or root repair and underwent clinically indicated gated or nongated MDCT of the aortic valve and aortic root were included in the present analysis. Patients with endocarditis were excluded. MDCT data of aortic valve anatomy and calcification and thoracic aorta dimensions were analyzed. Results The aortic valve and root was successfully repaired in 36 patients (55 ± 13 years; 61% male; median EuroSCORE II, 3.8%) whereas in 25 patients (56 ± 15 years; 52% male; median EuroSCORE II, 2.5%) repair was not attempted (n = 20) or valve repair was converted to aortic valve replacement during surgery (n = 5). In patients in whom repair was considered not possible or failed, there was a higher percentage of bicuspid aortic valves (48% vs 17%; P  = .019), more severe commissural calcification, and more severe annular calcification. Conclusion The degree of commissural and annular calcification of the aortic valve determined by MDCT is inversely related to the ability to perform surgical valve repair instead of replacement. Similarly, bicuspid valve anatomy predicts failure to perform repair.</description><identifier>ISSN: 1934-5925</identifier><identifier>EISSN: 1876-861X</identifier><identifier>DOI: 10.1016/j.jcct.2014.06.008</identifier><identifier>PMID: 25151922</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adult ; Aged ; Aorta, Thoracic - diagnostic imaging ; Aorta, Thoracic - surgery ; Aortic regurgitation ; Aortic root pathology ; Aortic root replacement ; Aortic Valve - abnormalities ; Aortic Valve - diagnostic imaging ; Aortic Valve - physiopathology ; Aortic Valve - surgery ; Aortic Valve Insufficiency - diagnostic imaging ; Aortic Valve Insufficiency - physiopathology ; Aortic Valve Insufficiency - surgery ; Aortic valve repair ; Aortography - methods ; Blood Vessel Prosthesis Implantation ; Calcinosis - diagnostic imaging ; Calcinosis - surgery ; Cardiac Surgical Procedures ; Cardiac-Gated Imaging Techniques ; Cardiovascular ; Computed tomography ; Female ; Heart Valve Prosthesis Implantation ; Humans ; Male ; Middle Aged ; Multidetector Computed Tomography ; Patient Selection ; Predictive Value of Tests ; Retrospective Studies ; Severity of Illness Index</subject><ispartof>Journal of cardiovascular computed tomography, 2014-07, Vol.8 (4), p.299-306</ispartof><rights>Society of Cardiovascular Computed Tomography</rights><rights>2014 Society of Cardiovascular Computed Tomography</rights><rights>Copyright © 2014 Society of Cardiovascular Computed Tomography. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c411t-af9a30347274b3435672fde4309fd398c12b37e507ab909b29c6bc45f522d9a23</citedby><cites>FETCH-LOGICAL-c411t-af9a30347274b3435672fde4309fd398c12b37e507ab909b29c6bc45f522d9a23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jcct.2014.06.008$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25151922$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Regeer, Madelien V., MD</creatorcontrib><creatorcontrib>Kamperidis, Vasileios, MD, MSc</creatorcontrib><creatorcontrib>Versteegh, Michel I.M., MD</creatorcontrib><creatorcontrib>Klautz, Robert J.M., MD, PhD</creatorcontrib><creatorcontrib>Scholte, Arthur J.H.A., MD, PhD</creatorcontrib><creatorcontrib>Bax, Jeroen J., MD, PhD</creatorcontrib><creatorcontrib>Schalij, Martin J., MD, PhD</creatorcontrib><creatorcontrib>Marsan, Nina Ajmone, MD, PhD</creatorcontrib><creatorcontrib>Delgado, Victoria, MD, PhD</creatorcontrib><title>Aortic valve and aortic root features in CT angiography in patients considered for aortic valve repair</title><title>Journal of cardiovascular computed tomography</title><addtitle>J Cardiovasc Comput Tomogr</addtitle><description>Abstract Background The underlying mechanism of aortic regurgitation and aortic valve and root characteristics are associated with the durability of surgical repair. Objective We investigated whether multidetector CT (MDCT) identifies the characteristics of the aortic valve and root that may be associated with the ability to perform successful surgical repair. Methods Sixty-one patients with aortic regurgitation and/or aortic root pathology who were evaluated for aortic valve or root repair and underwent clinically indicated gated or nongated MDCT of the aortic valve and aortic root were included in the present analysis. Patients with endocarditis were excluded. MDCT data of aortic valve anatomy and calcification and thoracic aorta dimensions were analyzed. Results The aortic valve and root was successfully repaired in 36 patients (55 ± 13 years; 61% male; median EuroSCORE II, 3.8%) whereas in 25 patients (56 ± 15 years; 52% male; median EuroSCORE II, 2.5%) repair was not attempted (n = 20) or valve repair was converted to aortic valve replacement during surgery (n = 5). In patients in whom repair was considered not possible or failed, there was a higher percentage of bicuspid aortic valves (48% vs 17%; P  = .019), more severe commissural calcification, and more severe annular calcification. Conclusion The degree of commissural and annular calcification of the aortic valve determined by MDCT is inversely related to the ability to perform surgical valve repair instead of replacement. Similarly, bicuspid valve anatomy predicts failure to perform repair.</description><subject>Adult</subject><subject>Aged</subject><subject>Aorta, Thoracic - diagnostic imaging</subject><subject>Aorta, Thoracic - surgery</subject><subject>Aortic regurgitation</subject><subject>Aortic root pathology</subject><subject>Aortic root replacement</subject><subject>Aortic Valve - abnormalities</subject><subject>Aortic Valve - diagnostic imaging</subject><subject>Aortic Valve - physiopathology</subject><subject>Aortic Valve - surgery</subject><subject>Aortic Valve Insufficiency - diagnostic imaging</subject><subject>Aortic Valve Insufficiency - physiopathology</subject><subject>Aortic Valve Insufficiency - surgery</subject><subject>Aortic valve repair</subject><subject>Aortography - methods</subject><subject>Blood Vessel Prosthesis Implantation</subject><subject>Calcinosis - diagnostic imaging</subject><subject>Calcinosis - surgery</subject><subject>Cardiac Surgical Procedures</subject><subject>Cardiac-Gated Imaging Techniques</subject><subject>Cardiovascular</subject><subject>Computed tomography</subject><subject>Female</subject><subject>Heart Valve Prosthesis Implantation</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Multidetector Computed Tomography</subject><subject>Patient Selection</subject><subject>Predictive Value of Tests</subject><subject>Retrospective Studies</subject><subject>Severity of Illness Index</subject><issn>1934-5925</issn><issn>1876-861X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kUtr3TAQRkVpaR7tH-iieNmNHT1tC0ogXNImEOiiKXQnZGmUyPG1XMm-cP99ZZx0kUVXEqNvzqAzCH0iuCKY1Bd91RszVxQTXuG6wrh9g05J29RlW5Pfb_NdMl4KScUJOkupx1g0BLfv0QkVRBBJ6SlyVyHO3hQHPRyg0KMt9FaIIcyFAz0vEVLhx2J3n58ffHiIeno8rpVJzx7GORUmjMlbiGALF-ILYUNGmLSPH9A7p4cEH5_Pc_Tr2_X97qa8-_H9dnd1VxpOyFxqJzXDjDe04R3jTNQNdRY4w9JZJltDaMcaELjRncSyo9LUneHCCUqt1JSdoy8bd4rhzwJpVnufDAyDHiEsSREhatqy7CVH6RY1MaQUwakp-r2OR0WwWv2qXq1-1epX4Vplv7np8zN_6fZg_7W8CM2Br1sA8i8PHqJKJksyYH2EDLPB_59_-ardDH70Rg9PcITUhyWO2Z8iKlGF1c91w-uCCceZmOf_BU0VoQY</recordid><startdate>20140701</startdate><enddate>20140701</enddate><creator>Regeer, Madelien V., MD</creator><creator>Kamperidis, Vasileios, MD, MSc</creator><creator>Versteegh, Michel I.M., MD</creator><creator>Klautz, Robert J.M., MD, PhD</creator><creator>Scholte, Arthur J.H.A., MD, PhD</creator><creator>Bax, Jeroen J., MD, PhD</creator><creator>Schalij, Martin J., MD, PhD</creator><creator>Marsan, Nina Ajmone, MD, PhD</creator><creator>Delgado, Victoria, MD, PhD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20140701</creationdate><title>Aortic valve and aortic root features in CT angiography in patients considered for aortic valve repair</title><author>Regeer, Madelien V., MD ; Kamperidis, Vasileios, MD, MSc ; Versteegh, Michel I.M., MD ; Klautz, Robert J.M., MD, PhD ; Scholte, Arthur J.H.A., MD, PhD ; Bax, Jeroen J., MD, PhD ; Schalij, Martin J., MD, PhD ; Marsan, Nina Ajmone, MD, PhD ; Delgado, Victoria, MD, PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c411t-af9a30347274b3435672fde4309fd398c12b37e507ab909b29c6bc45f522d9a23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aorta, Thoracic - diagnostic imaging</topic><topic>Aorta, Thoracic - surgery</topic><topic>Aortic regurgitation</topic><topic>Aortic root pathology</topic><topic>Aortic root replacement</topic><topic>Aortic Valve - abnormalities</topic><topic>Aortic Valve - diagnostic imaging</topic><topic>Aortic Valve - physiopathology</topic><topic>Aortic Valve - surgery</topic><topic>Aortic Valve Insufficiency - diagnostic imaging</topic><topic>Aortic Valve Insufficiency - physiopathology</topic><topic>Aortic Valve Insufficiency - surgery</topic><topic>Aortic valve repair</topic><topic>Aortography - methods</topic><topic>Blood Vessel Prosthesis Implantation</topic><topic>Calcinosis - diagnostic imaging</topic><topic>Calcinosis - surgery</topic><topic>Cardiac Surgical Procedures</topic><topic>Cardiac-Gated Imaging Techniques</topic><topic>Cardiovascular</topic><topic>Computed tomography</topic><topic>Female</topic><topic>Heart Valve Prosthesis Implantation</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Multidetector Computed Tomography</topic><topic>Patient Selection</topic><topic>Predictive Value of Tests</topic><topic>Retrospective Studies</topic><topic>Severity of Illness Index</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Regeer, Madelien V., MD</creatorcontrib><creatorcontrib>Kamperidis, Vasileios, MD, MSc</creatorcontrib><creatorcontrib>Versteegh, Michel I.M., MD</creatorcontrib><creatorcontrib>Klautz, Robert J.M., MD, PhD</creatorcontrib><creatorcontrib>Scholte, Arthur J.H.A., MD, PhD</creatorcontrib><creatorcontrib>Bax, Jeroen J., MD, PhD</creatorcontrib><creatorcontrib>Schalij, Martin J., MD, PhD</creatorcontrib><creatorcontrib>Marsan, Nina Ajmone, MD, PhD</creatorcontrib><creatorcontrib>Delgado, Victoria, MD, PhD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of cardiovascular computed tomography</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Regeer, Madelien V., MD</au><au>Kamperidis, Vasileios, MD, MSc</au><au>Versteegh, Michel I.M., MD</au><au>Klautz, Robert J.M., MD, PhD</au><au>Scholte, Arthur J.H.A., MD, PhD</au><au>Bax, Jeroen J., MD, PhD</au><au>Schalij, Martin J., MD, PhD</au><au>Marsan, Nina Ajmone, MD, PhD</au><au>Delgado, Victoria, MD, PhD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Aortic valve and aortic root features in CT angiography in patients considered for aortic valve repair</atitle><jtitle>Journal of cardiovascular computed tomography</jtitle><addtitle>J Cardiovasc Comput Tomogr</addtitle><date>2014-07-01</date><risdate>2014</risdate><volume>8</volume><issue>4</issue><spage>299</spage><epage>306</epage><pages>299-306</pages><issn>1934-5925</issn><eissn>1876-861X</eissn><abstract>Abstract Background The underlying mechanism of aortic regurgitation and aortic valve and root characteristics are associated with the durability of surgical repair. Objective We investigated whether multidetector CT (MDCT) identifies the characteristics of the aortic valve and root that may be associated with the ability to perform successful surgical repair. Methods Sixty-one patients with aortic regurgitation and/or aortic root pathology who were evaluated for aortic valve or root repair and underwent clinically indicated gated or nongated MDCT of the aortic valve and aortic root were included in the present analysis. Patients with endocarditis were excluded. MDCT data of aortic valve anatomy and calcification and thoracic aorta dimensions were analyzed. Results The aortic valve and root was successfully repaired in 36 patients (55 ± 13 years; 61% male; median EuroSCORE II, 3.8%) whereas in 25 patients (56 ± 15 years; 52% male; median EuroSCORE II, 2.5%) repair was not attempted (n = 20) or valve repair was converted to aortic valve replacement during surgery (n = 5). In patients in whom repair was considered not possible or failed, there was a higher percentage of bicuspid aortic valves (48% vs 17%; P  = .019), more severe commissural calcification, and more severe annular calcification. Conclusion The degree of commissural and annular calcification of the aortic valve determined by MDCT is inversely related to the ability to perform surgical valve repair instead of replacement. Similarly, bicuspid valve anatomy predicts failure to perform repair.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>25151922</pmid><doi>10.1016/j.jcct.2014.06.008</doi><tpages>8</tpages></addata></record>
fulltext fulltext
identifier ISSN: 1934-5925
ispartof Journal of cardiovascular computed tomography, 2014-07, Vol.8 (4), p.299-306
issn 1934-5925
1876-861X
language eng
recordid cdi_proquest_miscellaneous_1556283934
source MEDLINE; Access via ScienceDirect (Elsevier)
subjects Adult
Aged
Aorta, Thoracic - diagnostic imaging
Aorta, Thoracic - surgery
Aortic regurgitation
Aortic root pathology
Aortic root replacement
Aortic Valve - abnormalities
Aortic Valve - diagnostic imaging
Aortic Valve - physiopathology
Aortic Valve - surgery
Aortic Valve Insufficiency - diagnostic imaging
Aortic Valve Insufficiency - physiopathology
Aortic Valve Insufficiency - surgery
Aortic valve repair
Aortography - methods
Blood Vessel Prosthesis Implantation
Calcinosis - diagnostic imaging
Calcinosis - surgery
Cardiac Surgical Procedures
Cardiac-Gated Imaging Techniques
Cardiovascular
Computed tomography
Female
Heart Valve Prosthesis Implantation
Humans
Male
Middle Aged
Multidetector Computed Tomography
Patient Selection
Predictive Value of Tests
Retrospective Studies
Severity of Illness Index
title Aortic valve and aortic root features in CT angiography in patients considered for aortic valve repair
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T22%3A54%3A59IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Aortic%20valve%20and%20aortic%20root%20features%20in%20CT%20angiography%20in%20patients%20considered%20for%20aortic%20valve%20repair&rft.jtitle=Journal%20of%20cardiovascular%20computed%20tomography&rft.au=Regeer,%20Madelien%20V.,%20MD&rft.date=2014-07-01&rft.volume=8&rft.issue=4&rft.spage=299&rft.epage=306&rft.pages=299-306&rft.issn=1934-5925&rft.eissn=1876-861X&rft_id=info:doi/10.1016/j.jcct.2014.06.008&rft_dat=%3Cproquest_cross%3E1556283934%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1556283934&rft_id=info:pmid/25151922&rft_els_id=1_s2_0_S1934592514001622&rfr_iscdi=true