Green coffee polyphenols do not attenuate features of the metabolic syndrome and improve endothelial function in mice fed a high fat diet

•Coffee is one of the most widely consumed beverages in the Western world.•Coffee intake has been associated with reduced risk of many chronic diseases, including cardiovascular disease.•Green coffee bean extract did not protect against features of the metabolic syndrome in mice fed a high-fat diet....

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Veröffentlicht in:	Archives of biochemistry and biophysics 2014-10, Vol.559, p.46-52
Hauptverfasser:	Li Kwok Cheong, J.D., Croft, K.D., Henry, P.D., Matthews, V., Hodgson, J.M., Ward, N.C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta, Abdominal - drug effects Aorta, Abdominal - physiopathology Atherosclerosis Body Weight - drug effects Chlorogenic acid Coffee Coffee - chemistry Diet, High-Fat - adverse effects Endothelial dysfunction Endothelium, Vascular - drug effects Endothelium, Vascular - metabolism Endothelium, Vascular - pathology Glucose Tolerance Test Insulin Resistance Male Metabolic syndrome Metabolic Syndrome - drug therapy Metabolic Syndrome - etiology Metabolic Syndrome - metabolism Metabolic Syndrome - pathology Mice Mice, Inbred C57BL Oxidative Stress - drug effects Polyphenols - isolation & purification Polyphenols - pharmacology Polyphenols - therapeutic use Vasodilation - drug effects
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