CSL112 Enhances Biomarkers of Reverse Cholesterol Transport After Single and Multiple Infusions in Healthy Subjects

OBJECTIVE—The ability of apolipoprotein A-I (apoA-I) to transport cholesterol from atherosclerotic plaque is thought to underlie its inverse correlation with cardiovascular risk. To gauge the potential of infused apoA-I to transport cholesterol, we quantified cholesterol transport markers in human s...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Arteriosclerosis, thrombosis, and vascular biology thrombosis, and vascular biology, 2014-09, Vol.34 (9), p.2106-2114
Hauptverfasser:	Gille, Andreas, Easton, Rachael, D’Andrea, Denise, Wright, Samuel D, Shear, Charles L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Apolipoprotein A-I - metabolism ATP Binding Cassette Transporter 1 - blood Biological Transport Biomarkers Cholesterol - blood Cholesterol Esters - metabolism Cholesterol, HDL - blood Dose-Response Relationship, Drug Female Humans Infusions, Intravenous Lipoproteins, HDL - administration & dosage Lipoproteins, HDL - pharmacokinetics Lipoproteins, HDL - pharmacology Male Phosphatidylcholine-Sterol O-Acyltransferase - metabolism Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!