Role of Aldosterone Blockade in Resistant Hypertension

Summary Apparent treatment-resistant hypertension (aTRH), defined as uncontrolled blood pressure using 3 or more antihypertensive medications or controlled using 4 or more antihypertensive medications, affects approximately 30% of uncontrolled and 12% of controlled blood pressure (BP) patients. aTRH...

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Veröffentlicht in:	Seminars in nephrology 2014-05, Vol.34 (3), p.273-284
Hauptverfasser:	Egan, Brent M., MD, Li, Jiexiang, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	aldosterone aldosterone-antagonists Blood Pressure Determination Clinical Trials as Topic Drug Resistance Glomerular Filtration Rate - drug effects Humans hypertension Hypertension - drug therapy Insulin Resistance Kidney - metabolism Medication Adherence Mineralocorticoid Receptor Antagonists - therapeutic use Nephrology Sodium - metabolism Spironolactone - therapeutic use treatment resisitant hypertension
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