OASIS regulates chondroitin 6‐O‐sulfotransferase 1 gene transcription in the injured adult mouse cerebral cortex

Old astrocyte specifically induced substance (OASIS), a basic leucine zipper transcription factor of the cAMP response element binding/Activating transcription factor family, is induced in reactive astrocytes in vivo and has important roles in quality control of protein synthesis at the endoplasmic...

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Veröffentlicht in:	Journal of neurochemistry 2014-09, Vol.130 (5), p.612-625
Hauptverfasser:	Okuda, Hiroaki, Tatsumi, Kouko, Horii‐Hayashi, Noriko, Morita, Shoko, Okuda‐Yamamoto, Aya, Imaizumi, Kazunori, Wanaka, Akio
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals astrocyte Astrocytes - metabolism Blotting, Western Brain Injuries - genetics Brain Injuries - metabolism carbohydrate (chondroitin 6/keratan) sulfotransferase 3 Carbohydrate Sulfotransferases Cerebral Cortex - metabolism Chondroitin sulfate chondroitin sulfate proteoglycan Chondroitin Sulfate Proteoglycans - biosynthesis Chondroitin Sulfate Proteoglycans - genetics cortical injury Cyclic AMP Response Element-Binding Protein - metabolism Disease Models, Animal endoplasmic reticulum stress Enzymes Gene Expression Regulation - physiology Genes Immunohistochemistry Mice Mice, Inbred C57BL Mice, Knockout Nerve Tissue Proteins - metabolism Neurochemistry Neurons - metabolism OASIS Rats Real-Time Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction Rodents Sulfotransferases - biosynthesis Sulfotransferases - genetics Transcription factors Transcription, Genetic
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